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rs17036170(A;A)

From SNPedia

Elevated risk for drug induced liver injury with diclofenac
Is agenotype
ofrs17036170
GenePPARG
Chromosome3
Position12,288,912
mentionedby
Magnitude2
ReputeBad
Geno Mag Summary
(A;A) 2 Elevated risk for drug induced liver injury with diclofenac
(A;G) 1.9 Increased risk of drug induced liver injury with diclofenac
(G;G) 0 Normal risk of drug induced liver injury with diclofenac

This uncommon risk allele A was found in a GWAS to be associated with drug induced liver injury with diclofenac. OR = 11.3 (4.9–25.9) Replicability is uncertain, but individuals with this genotype should be aware of the potential of increased risk. The odds ratio above is probably for heterozygotes, and it is not clear if the homozygous AA is worse, if in fact the risk can be replicated.