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rs17110563

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs17110563(C;T)
Make rs17110563(T;T)
ReferenceGRCh38 38.1/141
Chromosome12
Position71972526
GeneTPH2
is asnp
is mentioned by
dbSNPrs17110563
ebirs17110563
HLIrs17110563
Exacrs17110563
Varsomers17110563
Maprs17110563
PheGenIrs17110563
hapmaprs17110563
1000 genomesrs17110563
hgdprs17110563
ensemblrs17110563
gopubmedrs17110563
geneviewrs17110563
scholarrs17110563
googlers17110563
pharmgkbrs17110563
gwascentralrs17110563
openSNPrs17110563
23andMers17110563
23andMe allrs17110563
SNP Nexus

SNPshotrs17110563
SNPdbers17110563
MSV3drs17110563
GWAS Ctlgrs17110563
Max Magnitude0
? (C;C) (C;T) (T;T) 28
rs17110563, also known as Pro206Ser, is a SNP in the TPH2 gene. The minor allele of this SNP yielded an odds ratio of 4.8 (CI:1.6-14.8) for increased risk for bipolar disorder in a study of 883 Russian patients.[PMID 17905754]
Neighborrs7963720
Distance120
OMIM607478
DescTRYPTOPHAN HYDROXYLASE 2; TPH2
Variant
Relatedalso


OMIM607478
Desc
Variant0003
Relatedalso


ClinVar
Risk rs17110563(T;T)
Alt rs17110563(T;T)
Reference rs17110563(C;C)
Significance Other
Disease Bipolar affective disorder
Variation info
Gene TPH2
CLNDBN Bipolar affective disorder, susceptibility to
Reversed 0
HGVS NC_000012.11:g.72366306C>T
CLNSRC OMIM Allelic Variant
CLNACC RCV000003314.2,



[PMID 18797398] Investigation of the tryptophan hydroxylase 2 gene in bipolar I disorder in the Romanian population.