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rs174550

From SNPedia

Orientationplus
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Make rs174550(C;C)
Make rs174550(C;T)
Make rs174550(T;T)
ReferenceGRCh38 38.1/141
Chromosome11
Position61804006
GeneFADS1
is asnp
is mentioned by
dbSNPrs174550
ebirs174550
HLIrs174550
Exacrs174550
Varsomers174550
Maprs174550
PheGenIrs174550
hapmaprs174550
1000 genomesrs174550
hgdprs174550
ensemblrs174550
gopubmedrs174550
geneviewrs174550
scholarrs174550
googlers174550
pharmgkbrs174550
gwascentralrs174550
openSNPrs174550
23andMers174550
23andMe allrs174550
SNP Nexus

SNPshotrs174550
SNPdbers174550
MSV3drs174550
GWAS Ctlgrs174550
GMAF0.3297
Max Magnitude
[PMID 21421807OA-icon.png] In a study conducted on 6,580 Nondiabetic Finnish Men, the glucose-increasing allele of rs174550 in FADS1 was significantly associated with high concentrations of very large and large HDL particles and nominally associated with low concentrations of all VLDL particles.
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 20081858OA-icon.png]
Trait Fasting glucose-related traits
Title New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Risk Allele T
P-val 5E-13
Odds Ratio None None



[PMID 21887289OA-icon.png] Glucose-Raising Genetic Variants in MADD and ADCY5 Impair Conversion of Proinsulin to Insulin

GWAS snp
PMID [PMID 21829377OA-icon.png]
Trait
Title Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium.
Risk Allele T
P-val 1E-57
Odds Ratio 0.0800 [NR] % increase
GWAS snp
PMID [PMID 22581228OA-icon.png]
Trait
Title A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Risk Allele
P-val 2E-9
Odds Ratio None None


GET Evidence
rs174550
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.21875
summary



[PMID 23396965OA-icon.png] Interaction between a common variant in FADS1 and erythrocyte polyunsaturated fatty acids on lipid profile in Chinese Hans.

GWAS snp
PMID [PMID 24823311OA-icon.png]
Trait Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid)
Title Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.
Risk Allele T
P-val 4E-140
Odds Ratio .05 [NR] unit increase
GWAS snp
PMID [PMID 24816252OA-icon.png]
Trait Blood metabolite levels
Title An atlas of genetic influences on human blood metabolites.
Risk Allele T
P-val 7E-24
Odds Ratio .04 [0.029-0.041] unit increase