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rs17482753

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 normal
(G;T) elevated triglycerides
(T;T) elevated triglycerides
ReferenceGRCh38 38.1/141
Chromosome8
Position19975135
is asnp
is mentioned by
dbSNPrs17482753
ebirs17482753
HLIrs17482753
Exacrs17482753
Varsomers17482753
Maprs17482753
PheGenIrs17482753
hapmaprs17482753
1000 genomesrs17482753
hgdprs17482753
ensemblrs17482753
gopubmedrs17482753
geneviewrs17482753
scholarrs17482753
googlers17482753
pharmgkbrs17482753
gwascentralrs17482753
openSNPrs17482753
23andMers17482753
23andMe allrs17482753
SNP Nexus

SNPshotrs17482753
SNPdbers17482753
MSV3drs17482753
GWAS Ctlgrs17482753
GMAF0.09412
Max Magnitude0
? (G;G) (G;T) (T;T) 28
Rs17482753
PubMed [PMID 17463246]
Affy Probeset SNP_A-2105269
Affy Orientation same
On GW 5.0 1
Alleles A/B G/T
Ancestral G
Population NEU
Allele T
Case Freq.
Control Freq. 0.1
Odds Ratio Het
Odds Ratio Hom
Odds Ratio All -
Disease Elevated HDL-Cholesterol (E-HDL)


rs17482753 increases susceptibility to Elevated HDL-Cholesterol for carriers of the T allele [PMID 17463246]

rs17482753 increases susceptibility to Elevated triglycerides for carriers of the T allele [PMID 17463246]

GWAS snp
PMID [PMID 20031538]
Trait HDL cholesterol
Title Genome-Wide Association Analysis of High-Density Lipoprotein Cholesterol in the Population-Based KORA Study Sheds New Light on Intergenic Regions
Risk Allele T
P-val 3E-11
Odds Ratio 2.02 [NR] mg/dl increase


[PMID 18179892OA-icon.png] Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.


[PMID 19041386OA-icon.png] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.


[PMID 19148283OA-icon.png] Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.


[PMID 19161620OA-icon.png] An open access database of genome-wide association results.


[PMID 19656773OA-icon.png] A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.


[PMID 20018038OA-icon.png] Evaluation of genetic risk scores for lipid levels using genome-wide markers in the Framingham Heart Study.


[PMID 20018072OA-icon.png] Different models and single-nucleotide polymorphisms signal the simulated weak gene-gene interaction for a quantitative trait using haplotype-based and mixed models testing.


[PMID 20370913OA-icon.png] Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham heart study data.

GWAS snp
PMID [PMID 24023261OA-icon.png]
Trait Lipid traits
Title THOC5: a novel gene involved in HDL-cholesterol metabolism.
Risk Allele T
P-val 6E-10
Odds Ratio -.24 unit decrease