Have questions? Visit https://www.reddit.com/r/SNPedia

rs17632542

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 0 common in complete genomics
Make rs17632542(C;C)
Make rs17632542(C;T)
ReferenceGRCh38 38.1/141
Chromosome19
Position50858501
GeneKLK3
is asnp
is mentioned by
dbSNPrs17632542
ebirs17632542
HLIrs17632542
Exacrs17632542
Varsomers17632542
Maprs17632542
PheGenIrs17632542
hapmaprs17632542
1000 genomesrs17632542
hgdprs17632542
ensemblrs17632542
gopubmedrs17632542
geneviewrs17632542
scholarrs17632542
googlers17632542
pharmgkbrs17632542
gwascentralrs17632542
openSNPrs17632542
23andMers17632542
23andMe allrs17632542
SNP Nexus

SNPshotrs17632542
SNPdbers17632542
MSV3drs17632542
GWAS Ctlgrs17632542
GMAF0.03168
Max Magnitude0
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 21160077OA-icon.png]
Trait
Title Genetic Correction of PSA Values Using Sequence Variants Associated with PSA Levels
Risk Allele T
P-val 3E-46
Odds Ratio 39.1000 [NR] % increase


[PMID 21465221OA-icon.png] Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript

[PMID 21318478OA-icon.png] Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels.


GET Evidence
KLK3-I179T
aa_change Ile179Thr
aa_change_short I179T
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.0390625
summary



[PMID 23359319OA-icon.png] Genome-wide Association Study Identifies Loci at ATF7IP and KLK2 Associated with Percentage of Circulating Free PSA


[PMID 23937305OA-icon.png] Validation of association of genetic variants at 10q with prostate-specific antigen (PSA) levels in men at high risk for prostate cancer


[PMID 24345439OA-icon.png] Prostate cancer risk alleles are associated with prostate cancer tumor volume and prostate size


[PMID 23246478OA-icon.png] Personalized prostate specific antigen testing using genetic variants may reduce unnecessary prostate biopsies.

GWAS snp
PMID [PMID 24753544OA-icon.png]
Trait Prostate cancer
Title Genetic variation in prostate-specific antigen-detected prostate cancer and the effect of control selection on genetic association studies.
Risk Allele T
P-val 2E-28
Odds Ratio .73 [0.60-0.86] unit increase
GWAS snp
PMID [PMID 24740154OA-icon.png]
Trait Prostate cancer (early onset)
Title Genome-wide association scan for variants associated with early-onset prostate cancer.
Risk Allele T
P-val 1E-7
Odds Ratio 1.85 [1.61-2.09]