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rs17708472

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common in clinvar
Make rs17708472(A;A)
Make rs17708472(A;G)
ReferenceGRCh38 38.1/141
Chromosome16
Position31094032
GeneVKORC1
is asnp
is mentioned by
dbSNPrs17708472
ebirs17708472
HLIrs17708472
Exacrs17708472
Varsomers17708472
Maprs17708472
PheGenIrs17708472
hapmaprs17708472
1000 genomesrs17708472
hgdprs17708472
ensemblrs17708472
gopubmedrs17708472
geneviewrs17708472
scholarrs17708472
googlers17708472
pharmgkbrs17708472
gwascentralrs17708472
openSNPrs17708472
23andMers17708472
23andMe allrs17708472
SNP Nexus

SNPshotrs17708472
SNPdbers17708472
MSV3drs17708472
GWAS Ctlgrs17708472
GMAF0.118
Max Magnitude0
? (A;A) (A;G) (G;G) 28
[PMID 21127708OA-icon.png] Genetic Variation of VKORC1 and CYP4F2 Genes Related to Warfarin Maintenance Dose in Patients with Myocardial Infarction


[PMID 22118051] Genetic variants in CYP (-1A2, -2C9, -2C19, -3A4 and -3A5), VKORC1 and ABCB1 genes in a black South African population: a window into diversity


[PMID 18252229OA-icon.png] Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations.


[PMID 18855533OA-icon.png] VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans.


[PMID 19436136OA-icon.png] Association of sequence variations in vitamin K epoxide reductase and gamma-glutamyl carboxylase genes with biochemical measures of vitamin K status.


GET Evidence
rs17708472
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.15625
summary



[PMID 23662025OA-icon.png] Genetic variation and haplotype structure of the gene Vitamin K epoxide reductase complex, subunit 1 in the Tamilian population


ClinVar
Risk rs17708472(A;A)
Alt rs17708472(A;A)
Reference rs17708472(G;G)
Significance Drug-response
Disease warfarin response - Dosage
Variation info
Gene VKORC1
CLNDBN warfarin response - Dosage
Reversed 0
HGVS NC_000016.9:g.31105353G>A
CLNSRC PharmGKB Clinical Annotation PharmGKB
CLNACC RCV000211198.1,