Have questions? Visit https://www.reddit.com/r/SNPedia

rs1780329

From SNPedia

Orientationminus
Stabilizedminus
Make rs1780329(G;G)
Make rs1780329(G;T)
Make rs1780329(T;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position21576457
GeneALPL
is asnp
is mentioned by
dbSNPrs1780329
ebirs1780329
HLIrs1780329
Exacrs1780329
Varsomers1780329
Maprs1780329
PheGenIrs1780329
hapmaprs1780329
1000 genomesrs1780329
hgdprs1780329
ensemblrs1780329
gopubmedrs1780329
geneviewrs1780329
scholarrs1780329
googlers1780329
pharmgkbrs1780329
gwascentralrs1780329
openSNPrs1780329
23andMers1780329
23andMe allrs1780329
SNP Nexus

SNPshotrs1780329
SNPdbers1780329
MSV3drs1780329
GWAS Ctlgrs1780329
GMAF0.3159
Max Magnitude
? (G;G) (G;T) (T;T) 28
[PMID 17195227] A study of 201 Canadian ankylosing spondylitis families concluded the ALPL (TNAP) haplotype G-G-T for SNPs rs3767155-rs3738099-rs1780329, respectively, is significantly associated with the disease but only in men.

[PMID 18769922] A study of 353 Chinese ankylosing spondylitis patients found no significant difference in allele, genotype or haplotype frequencies for this SNP in either case-control or family-based association studies, which indicated that the TNAP (also known as ALPL) gene is unlikely to play a major role in the susceptibility to ankylosing spondylitis in the Chinese Han population.