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rs1781735

From SNPedia

Orientationminus
Make rs1781735(A;A)
Make rs1781735(A;C)
Make rs1781735(C;C)
ReferenceGRCh38.p2 38.2/147
Chromosome6
Position38704303
GeneGLO1
is asnp
is mentioned by
dbSNPrs1781735
ebirs1781735
HLIrs1781735
Exacrs1781735
Varsomers1781735
Maprs1781735
PheGenIrs1781735
hapmaprs1781735
1000 genomesrs1781735
hgdprs1781735
ensemblrs1781735
gopubmedrs1781735
geneviewrs1781735
scholarrs1781735
googlers1781735
pharmgkbrs1781735
gwascentralrs1781735
openSNPrs1781735
23andMers1781735
23andMe allrs1781735
SNP Nexus

SNPshotrs1781735
SNPdbers1781735
MSV3drs1781735
GWAS Ctlgrs1781735
Max Magnitude
? (A;A) (A;C) (C;C) 28

[PMID 27000251] Role of glyoxalase I gene polymorphisms in late-onset epilepsy and drug-resistant epilepsy rs1781735 is a perfect proxy for rs1049346 with the G allele of rs1781735 corresponding to the C allele of rs1049346.The CC genotype of rs1049346 protects against late-onset epilepsy and drug resistant epilepsy (combined cohort, TT+TC/CC 2.645 p=0.000, and 3.049, p=0.001, respectively).

The presence of the TAC/AAT haplotypes (rs1130534-rs4746-rs1049346) may be used as a marker of predisposition to/protection against drug resistant epilepsy (combined cohorts, p=0.010 and 0.000 respectively. ORs are not provided ).