Have questions? Visit https://www.reddit.com/r/SNPedia

rs179008

From SNPedia

Orientationplus
Stabilizedplus
Make rs179008(A;A)
Make rs179008(A;T)
Make rs179008(T;T)
ReferenceGRCh38 38.1/141
ChromosomeX
Position12885540
GeneTLR7
is asnp
is mentioned by
dbSNPrs179008
ebirs179008
HLIrs179008
Exacrs179008
Varsomers179008
Maprs179008
PheGenIrs179008
hapmaprs179008
1000 genomesrs179008
hgdprs179008
ensemblrs179008
gopubmedrs179008
geneviewrs179008
scholarrs179008
googlers179008
pharmgkbrs179008
gwascentralrs179008
openSNPrs179008
23andMers179008
23andMe allrs179008
SNP Nexus

SNPshotrs179008
SNPdbers179008
MSV3drs179008
GWAS Ctlgrs179008
GMAF0.1518
Max Magnitude
? (A;A) (A;T) (T;T) 28

[PMID 19473567] Investigation of TLR5 and TLR7 as candidate genes for susceptibility to systemic lupus erythematosus


[PMID 20595247] Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients

[PMID 20872712] Toll-like receptor 7 rs179008/Gln11Leu gene variants in chronic hepatitis C virus infection


[PMID 18385087] Toll-like receptor polymorphisms and age-related macular degeneration.


[PMID 18682521] Association analysis identifies TLR7 and TLR8 as novel risk genes in asthma and related disorders.


[PMID 19505919OA-icon.png] Toll-like receptor signaling pathway variants and prostate cancer mortality.


[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.


[PMID 22065095] TLR7/8/9 polymorphisms and their associations in systemic lupus erythematosus patients from southern Brazil.


GET Evidence
TLR7-Q11L
aa_change Gln11Leu
aa_change_short Q11L
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.180801
summary



[PMID 24071890] TLR7 Gln11Leu single nucleotide polymorphism in patients with sarcoidosis


[PMID 25633712] Resiquimod as an Immunologic Adjuvant for NY-ESO-1 Protein Vaccination in Patients with High Risk Melanoma


[PMID 26556041] TLR7 Gln11Leu single nucleotide polymorphism and response to treatment with imiquimod in patients with basal cell carcinoma: a pilot study