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rs1793004

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) increased risk for Crohn's disease
(C;G)  ?
(G;G) 0.89x decreased risk for Crohn's disease
ReferenceGRCh38 38.1/141
Chromosome11
Position20677383
GeneNELL1
is asnp
is mentioned by
dbSNPrs1793004
ebirs1793004
HLIrs1793004
Exacrs1793004
Varsomers1793004
Maprs1793004
PheGenIrs1793004
hapmaprs1793004
1000 genomesrs1793004
hgdprs1793004
ensemblrs1793004
gopubmedrs1793004
geneviewrs1793004
scholarrs1793004
googlers1793004
pharmgkbrs1793004
gwascentralrs1793004
openSNPrs1793004
23andMers1793004
23andMe allrs1793004
SNP Nexus

SNPshotrs1793004
SNPdbers1793004
MSV3drs1793004
GWAS Ctlgrs1793004
GMAF0.3512
Max Magnitude
? (C;C) (C;G) (G;G) 28
rs1793004 is a SNP in the NELL1 gene that was found in a genome-wide association study to be associated with Crohn's disease.

In several European populations, the most common allele, rs1793004(C), was associated with increased risk for Crohn's disease. Conversely, the odds ratio (pooled over several populations) for the minor allele, rs1793004(G), was 0.89 (CI: 0.69-1.14, p=0.0037).[PMID 17684544OA-icon.png]

GWAS
SNP rs1793004
PubMedID [PMID 17684544OA-icon.png]
Condition Irritable bowel syndrome
Gene NELL1
Risk Allele
pValue 3.00E-006
OR 1.3
95% CI 1.12-1.52



GET Evidence
rs1793004
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.703125
summary