rs1799768
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (-;-) | 0 |
| Make rs1799768(-;G) |
| Make rs1799768(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 101126425 |
| Gene | SERPINE1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1799768 |
| dbSNP (classic) | rs1799768 |
| ClinGen | rs1799768 |
| ebi | rs1799768 |
| HLI | rs1799768 |
| Exac | rs1799768 |
| Gnomad | rs1799768 |
| Varsome | rs1799768 |
| LitVar | rs1799768 |
| Map | rs1799768 |
| PheGenI | rs1799768 |
| Biobank | rs1799768 |
| 1000 genomes | rs1799768 |
| hgdp | rs1799768 |
| ensembl | rs1799768 |
| geneview | rs1799768 |
| scholar | rs1799768 |
| rs1799768 | |
| pharmgkb | rs1799768 |
| gwascentral | rs1799768 |
| openSNP | rs1799768 |
| 23andMe | rs1799768 |
| SNPshot | rs1799768 |
| SNPdbe | rs1799768 |
| MSV3d | rs1799768 |
| GWAS Ctlg | rs1799768 |
| GMAF | 0.4683 |
| Max Magnitude | 0 |
This SNP is tightly linked to, and therefore please go to, rs1799889 for related information (the PAI1 or PAI-1 4G/5G deletion/insertion), although according to dbSNP they have different genomic loci, this SNP is located at 101126425 and the rs1799889 SNP at 101126430.
[PMID 19619703
] Association of genetic variants with the metabolic syndrome in 20,806 white women: The women's health genome study
[PMID 20549826] SERPINE1 intron polymorphisms affecting gene expression are associated with diffuse-type gastric cancer susceptibility
[PMID 21291465] The association of genetic polymorphisms with cerebral palsy: a meta-analysis
[PMID 21824047] Genetic polymorphisms associated with steroids metabolism and insulin action in polycystic ovary syndrome
[PMID 22134139] 4G/5G Polymorphism of the Plasminogen Activator Inhibitor-1 Gene Is Associated with Multiple Organ Dysfunction in Critically Ill Patients
[PMID 16356191] Regulatory polymorphisms in extracellular matrix protease genes and susceptibility to rheumatoid arthritis: a case-control study.
[PMID 16846490] Lemierre's syndrome and genetic polymorphisms: a case report.
[PMID 17107626] Comparison of PrASE and Pyrosequencing for SNP Genotyping.
[PMID 17207964] Epistatic effects of polymorphisms in genes from the renin-angiotensin, bradykinin, and fibrinolytic systems on plasma t-PA and PAI-1 levels.
[PMID 18513389] New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background.
[PMID 18603647] Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response.
[PMID 18805939] Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.
[PMID 18936436] Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.
[PMID 18953568] Male-female differences in the genetic regulation of t-PA and PAI-1 levels in a Ghanaian population.
[PMID 19131662] A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
[PMID 19263529] Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach.
[PMID 19330901] Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study.
[PMID 19559392] A candidate gene association study of 77 polymorphisms in migraine.
[PMID 19587357] A systematic meta-analysis of genetic association studies for diabetic retinopathy.
[PMID 20413122] Soluble fibre (Plantago ovata husk) reduces plasma low-density lipoprotein (LDL) cholesterol, triglycerides, insulin, oxidised LDL and systolic blood pressure in hypercholesterolaemic patients: A randomised trial.
[PMID 21304999] Epistatic interactions in genetic regulation of t-PA and PAI-1 levels in a Ghanaian population.
[PMID 22388798] Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.
[PMID 23225235] Association between the rs6950982 polymorphism near the SERPINE1 gene and blood pressure and lipid parameters in a high-cardiovascular-risk population: interaction with Mediterranean diet.
[PMID 26537299] SERPINE1 rs1799768 polymorphism contributes to sepsis risk and mortality
[PMID 30996113] Association between genetic polymorphisms and osteonecrosis in steroid treatment populations: a detailed stratified and dose-response meta-analysis.
