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rs1799913

From SNPedia

heroin addiction in hispanics
Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 1.1 Hispanics may be at increased risk of heroin addiction.
Make rs1799913(A;A)
Make rs1799913(A;C)
ReferenceGRCh38 38.1/141
Chromosome11
Position18025708
GeneTPH1
is asnp
is mentioned by
dbSNPrs1799913
ebirs1799913
HLIrs1799913
Exacrs1799913
Varsomers1799913
Maprs1799913
PheGenIrs1799913
hapmaprs1799913
1000 genomesrs1799913
hgdprs1799913
ensemblrs1799913
gopubmedrs1799913
geneviewrs1799913
scholarrs1799913
googlers1799913
pharmgkbrs1799913
gwascentralrs1799913
openSNPrs1799913
23andMers1799913
23andMe allrs1799913
SNP Nexus

SNPshotrs1799913
SNPdbers1799913
MSV3drs1799913
GWAS Ctlgrs1799913
GMAF0.3581
Max Magnitude1.1
commonly referred to as A779C

Only for Hispanics, individuals who have a genoset composed of rs1799913(C;C) and rs7963720(T;T) are reported to be at 14x higher risk for developing heroin addiction (CI:0.83-244.63, p=0.012).[PMID 18181017]

Again, only for Hispanics, individuals having a genoset composed of rs1799913(C;C) and rs4290270(T;T) are reported to be at 9x higher risk for developing heroin addiction (CI:0.5-153, p=0.063).[PMID 18181017]

Neighborrs1800532
Distance561
OMIM608516
DescMAJOR DEPRESSIVE DISORDER; MDD
Variant
Relatedalso
OMIM191060
DescTRYPTOPHAN HYDROXYLASE 1; TPH1
Variant
Relatedalso
[PMID 17521439OA-icon.png] Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach.

[PMID 20580984] Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers.