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rs1799978

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0 common in clinvar
Make rs1799978(A;G)
Make rs1799978(G;G)
ReferenceGRCh38 38.1/141
Chromosome11
Position113475629
GeneDRD2
is asnp
is mentioned by
dbSNPrs1799978
ebirs1799978
HLIrs1799978
Exacrs1799978
Varsomers1799978
Maprs1799978
PheGenIrs1799978
hapmaprs1799978
1000 genomesrs1799978
hgdprs1799978
ensemblrs1799978
gopubmedrs1799978
geneviewrs1799978
scholarrs1799978
googlers1799978
pharmgkbrs1799978
gwascentralrs1799978
openSNPrs1799978
23andMers1799978
23andMe allrs1799978
SNP Nexus

SNPshotrs1799978
SNPdbers1799978
MSV3drs1799978
GWAS Ctlgrs1799978
GMAF0.1051
Max Magnitude0
? (A;A) (A;G) (G;G) 28

[PMID 19373123] Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution



[PMID 19512960] Genetic diagnostics of functional variants of the human dopamine D2 receptor gene


[PMID 18305461OA-icon.png] Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety.

[PMID 18330705OA-icon.png] Physiogenomic analysis of localized FMRI brain activity in schizophrenia.

[PMID 19968402OA-icon.png] Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: an exploratory study with d-amphetamine in healthy participants.

[PMID 21162693OA-icon.png] Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction.


GET Evidence
rs1799978
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.164062
summary



[PMID 23828101OA-icon.png] Impulsivity and genetic variants in DRD2 and ANKK1 moderate longitudinal associations between sleep problems and overweight from ages 5 to 11.


ClinVar
Risk rs1799978(G;G)
Alt rs1799978(G;G)
Reference rs1799978(A;A)
Significance Drug-response
Disease risperidone response - Efficacy
Variation info
Gene DRD2
CLNDBN risperidone response - Efficacy
Reversed 1
HGVS NC_000011.9:g.113346351T>C
CLNSRC PharmGKB Clinical Annotation PharmGKB
CLNACC RCV000211152.1,