Have questions? Visit https://www.reddit.com/r/SNPedia

rs1800449

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(G;G) 0 common in clinvar
Make rs1800449(A;A)
Make rs1800449(A;G)
ReferenceGRCh38 38.1/142
Chromosome5
Position122077513
GeneLOX
is asnp
is mentioned by
dbSNPrs1800449
ebirs1800449
HLIrs1800449
Exacrs1800449
Varsomers1800449
Maprs1800449
PheGenIrs1800449
hapmaprs1800449
1000 genomesrs1800449
hgdprs1800449
ensemblrs1800449
gopubmedrs1800449
geneviewrs1800449
scholarrs1800449
googlers1800449
pharmgkbrs1800449
gwascentralrs1800449
openSNPrs1800449
23andMers1800449
23andMe allrs1800449
SNP Nexus

SNPshotrs1800449
SNPdbers1800449
MSV3drs1800449
GWAS Ctlgrs1800449
GMAF0.1667
Max Magnitude0
? (A;A) (A;G) (G;G) 28
OMIM153455
DescLYSYL OXIDASE POLYMORPHISM
Variant0001
Relatedalso
[PMID 19654310OA-icon.png] A Loss-of-Function Polymorphism in the Propeptide Domain of the LOX Gene and Breast Cancer


[PMID 20929399] Lysyl Oxidase 473 G>A Polymorphism and Breast Cancer Susceptibility in Chinese Han Population


[PMID 22533780] Lysyl Oxidase G473A Polymorphism Is Associated with Increased Risk of Ovarian Cancer


[PMID 22661479OA-icon.png] Variation in the Lysyl Oxidase (LOX) Gene Is Associated with Keratoconus in Family-Based and Case-Control Studies


ClinVar
Risk rs1800449(A;A)
Alt rs1800449(A;A)
Reference rs1800449(G;G)
Significance Non-pathogenic
Disease LYSYL OXIDASE POLYMORPHISM
Variation info
Gene LOX
CLNDBN LYSYL OXIDASE POLYMORPHISM
Reversed 1
HGVS NC_000005.9:g.121413208C>T
CLNSRC OMIM Allelic Variant
CLNACC RCV000015437.2,



[PMID 21995629] Lysyl oxidase G473A polymorphism is closely associated with susceptibility to gastric cancer in a South Korean population.


GET Evidence
LOX-R158Q
aa_change Arg158Gln
aa_change_short R158Q
impact benign
qualified_impact Insufficiently evaluated benign
overall_frequency 0.1725
summary



[PMID 22722997] Lysyl oxidase polymorphisms and ischemic stroke--a case control study.


[PMID 25141126OA-icon.png] Association of the G473A Polymorphism and Expression of Lysyl Oxidase with Breast Cancer Risk and Survival in European Women: A Hospital-Based Case-Control Study