rs1800566(C;T)
From SNPedia
| Possible Lower Lung Cancer risk |
| Is a | genotype |
| of | rs1800566 |
| Gene | NQO1 |
| Chromosome | 16 |
| Position | 69,711,242 |
| mentioned | by |
| Magnitude | 1.8 |
| Repute | Good |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in clinvar |
| (C;T) | 1.8 | Possible Lower Lung Cancer risk |
| (T;T) | 3.1 | Benzene toxicity; cancer risks |
rs1800566 may decrease susceptibility to Lung Cancer 0.48 times for heterozygotes (CT) due to the presence of the T allele reducing the rate at which the pro-carcinogenic activating NOD1 enzyme operates [PMID 15498787]
