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rs1800750

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) higher acute otitis risk
(A;G) normal risk
(G;G) 0 normal risk
ReferenceGRCh38 38.1/141
Chromosome6
Position31575186
GeneTNF
is asnp
is mentioned by
dbSNPrs1800750
ebirs1800750
HLIrs1800750
Exacrs1800750
Varsomers1800750
Maprs1800750
PheGenIrs1800750
hapmaprs1800750
1000 genomesrs1800750
hgdprs1800750
ensemblrs1800750
gopubmedrs1800750
geneviewrs1800750
scholarrs1800750
googlers1800750
pharmgkbrs1800750
gwascentralrs1800750
openSNPrs1800750
23andMers1800750
23andMe allrs1800750
SNP Nexus

SNPshotrs1800750
SNPdbers1800750
MSV3drs1800750
GWAS Ctlgrs1800750
GMAF0.01331
Max Magnitude0
? (A;A) (A;G) (G;G) 28
rs1800750, a SNP located at position -376 of the TNF gene, has been linked to increased risk for recurrent acute otitis in a study of 348 children. The (adjusted) odds ratio is 3.06 for (G;G) genotypes (p=0.07).[PMID 17908769]
Neighborrs1799724
Distance481
Neighborrs1800629
Distance68
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[PMID 22808100OA-icon.png] Functional differences exist between TNFalpha promoters encoding the common -237G SNP and the rarer HLA-B*5701-linked A variant.


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