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From SNPedia

Make rs1801132(C;C)
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ReferenceGRCh38 38.1/141
is asnp
is mentioned by
1000 genomesrs1801132
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GWAS Ctlgrs1801132
Max Magnitude
? (C;C) (C;G) (G;G) 28

[PMID 18680103] Comparison of genetic risk in three candidate genes (TCF7L2, PPARG, KCNJ11) with traditional risk factors for type 2 diabetes in a population-based study--the HUNT study

[PMID 19673915] Role of the oestrogen receptor (ESR1 PvuII and ESR1 325 C-->G) and progesterone receptor (PROGINS) polymorphisms in genetic susceptibility to migraine in a North Indian population

[PMID 20046055] Association of the G2014G genotype in estrogen receptor 1 gene with failure of the mifepristone-induced termination of early pregnancy

[PMID 19654868OA-icon.png] Genetic polymorphisms of estrogen receptors alpha and beta and the risk of developing prostate cancer

[PMID 20109228OA-icon.png] Haplotypes of intron 4 of the estrogen receptor alpha gene and hip fractures: a replication study in Caucasians

[PMID 20383761] Estrogen Receptor Alpha Polymorphisms and the Risk of Malignancies

[PMID 20172949OA-icon.png] Polymorphisms of estrogen receptors and risk of biliary tract cancers and gallstones: a population-based study in Shanghai, China

[PMID 20429621] Estrogen receptor alpha polymorphisms: correlation with clinicopathological parameters in breast cancer

[PMID 21528353] Genetic variants of 6q25 and breast cancer susceptibility: a two-stage fine mapping study in a Chinese population

[PMID 22511967OA-icon.png] Potential Role of Aromatase over Estrogen Receptor Gene Polymorphisms in Migraine Susceptibility: A Case Control Study from North India

[PMID 15113403OA-icon.png] Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis.

[PMID 15157284OA-icon.png] Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes.

[PMID 15217512OA-icon.png] Oestrogen receptor alpha gene haplotype and postmenopausal breast cancer risk: a case control study.

[PMID 16292600] Association analysis of estrogen receptor alpha gene polymorphisms with cross-sectional geometry of the femoral neck in Caucasian nuclear families.

[PMID 17116097] Testing of variants of the MTHFR and ESR1 genes in 1798 Finnish individuals fails to confirm the association with migraine with aura.

[PMID 17268813] Estrogen receptor alpha haplotypes and breast cancer risk in older Caucasian women.

[PMID 17609999] Association of progesterone receptor with migraine-associated vertigo.

[PMID 18053221OA-icon.png] Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis--a cohort study.

[PMID 18271972OA-icon.png] ESR1 and EGF genetic variation in relation to breast cancer risk and survival.

[PMID 18350145OA-icon.png] Association of the estrogen receptor 1 (ESR1) gene with body height in adult males from two Swedish population cohorts.

[PMID 18445666OA-icon.png] Variation in estrogen-related genes associated with cardiovascular phenotypes and circulating estradiol, testosterone, and dehydroepiandrosterone sulfate levels.

[PMID 18450649OA-icon.png] ESR1 polymorphism is associated with plasma lipid and apolipoprotein levels in Caucasians of the Rochester Family Heart Study.

[PMID 18511131] Estrogen receptor gene 1 variants are not associated with suicidal behavior.

[PMID 18636479OA-icon.png] Common genetic influences underlie comorbidity of migraine and endometriosis.

[PMID 18787887OA-icon.png] Genetic variation in candidate osteoporosis genes, bone mineral density, and fracture risk: the study of osteoporotic fractures.

[PMID 18990228OA-icon.png] Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study.

[PMID 19175383] Lack of association of hormone receptor polymorphisms with migraine.

[PMID 19194457OA-icon.png] Association between arterial stiffness and variations in oestrogen-related genes.

[PMID 19218192OA-icon.png] Genetic risk factors for portopulmonary hypertension in patients with advanced liver disease.

[PMID 19319135OA-icon.png] Common genetic variability in ESR1 and EGF in relation to endometrial cancer risk and survival.

[PMID 19375130OA-icon.png] Estrogen receptor 1 gene polymorphisms and decreased risk of obesity in women.

[PMID 19693267OA-icon.png] Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.

[PMID 19760036] Potentially functional polymorphisms in ESR1 and breast cancer risk: a meta-analysis.

[PMID 19884274OA-icon.png] The relationship of estrogen receptor-alpha and -beta genes with osteoarthritis of the hand.

[PMID 19941161] Combined genetic effect of CDK7 and ESR1 polymorphisms on breast cancer.

[PMID 21429951] Quantitative trait analysis suggests polymorphisms of estrogen-related genes regulate human sperm concentrations and motility.

[PMID 22011627] Genetic polymorphisms in estrogen receptors and sexual dimorphism in fat redistribution in HIV-infected patients on HAART.

[PMID 22324545] Are polymorphisms in oestrogen receptors genes associated with lipid levels in response to hormone therapy?

GET Evidence
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.813348

[PMID 25228414OA-icon.png] Variants of estrogen-related genes and breast cancer risk in European and African American women

[PMID 26434778OA-icon.png] Association Between ESR1 PvuII, XbaI, and P325P Polymorphisms and Breast Cancer Susceptibility: A Meta-Analysis