Have questions? Visit https://www.reddit.com/r/SNPedia

rs1801133(C;T)

From SNPedia

1 copy of C677T allele of MTHFR = 60% efficiency in processing folic acid = could have somewhat elevated homocysteine and low B12 and folate levels
Is agenotype
ofrs1801133
GeneMTHFR
Chromosome1
Position11,796,321
Merged fromRs59514310
mentionedby
Magnitude2.5
ReputeBad
Geno Mag Summary
(C;C) 0 Common genotype: normal homocysteine levels
(C;T) 2.5 1 copy of C677T allele of MTHFR = 60% efficiency in processing folic acid = could have somewhat elevated homocysteine and low B12 and folate levels
(T;T) 3 homozygous for C677T of MTHFR = 10-20% efficiency in processing folic acid = high homocysteine, low B12 and folate levels

It is found in approximately

  • 48% of Hispanic Americans
  • 45% of Caucasian Americans
  • 45% of Japanese
  • 37% of Germans
  • 29% of Asians
  • 24% of African Americans
  • 12% of Sub-Saharan Africans