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rs1801195

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common in clinvar
Make rs1801195(G;T)
Make rs1801195(T;T)
ReferenceGRCh38 38.1/141
Chromosome8
Position31141764
GeneWRN
is asnp
is mentioned by
dbSNPrs1801195
ebirs1801195
HLIrs1801195
Exacrs1801195
Varsomers1801195
Maprs1801195
PheGenIrs1801195
hapmaprs1801195
1000 genomesrs1801195
hgdprs1801195
ensemblrs1801195
gopubmedrs1801195
geneviewrs1801195
scholarrs1801195
googlers1801195
pharmgkbrs1801195
gwascentralrs1801195
openSNPrs1801195
23andMers1801195
23andMe allrs1801195
SNP Nexus

SNPshotrs1801195
SNPdbers1801195
MSV3drs1801195
GWAS Ctlgrs1801195
Merged fromRs2725362
GMAF0.4706
Max Magnitude0
? (G;G) (G;T) (T;T) 28
[PMID 16857995OA-icon.png] Risk of non-Hodgkin lymphoma (NHL) in relation to germline variation in DNA repair and related genes.

[PMID 17366557OA-icon.png] A genome-wide linkage scan for cleft lip and cleft palate identifies a novel locus on 8p11-23.

[PMID 18194558OA-icon.png] A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples.

[PMID 18978339OA-icon.png] Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity.

[PMID 19945966] Colorectal cancer and polymorphisms in DNA repair genes WRN, RMI1 and BLM.

GET Evidence
WRN-L1074F
aa_change Leu1074Phe
aa_change_short L1074F
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.466351
summary


[PMID 23619945OA-icon.png] Polymorphisms in DNA repair pathway genes, body mass index, and risk of non-Hodgkin lymphoma.

ClinVar
Risk rs1801195(T;T)
Alt rs1801195(T;T)
Reference rs1801195(G;G)
Significance Probable-non-pathogenic
Disease not specified
Variation info
Gene WRN
CLNDBN not specified
Reversed 0
HGVS NC_000008.10:g.30999280G>T
CLNSRC ClinVar University of Chicago
CLNACC RCV000118877.3,