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rs1801673

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 common in complete genomics
Make rs1801673(A;T)
Make rs1801673(T;T)
ReferenceGRCh38 38.1/141
Chromosome11
Position108304736
GeneATM
is asnp
is mentioned by
dbSNPrs1801673
ebirs1801673
HLIrs1801673
Exacrs1801673
Varsomers1801673
Maprs1801673
PheGenIrs1801673
hapmaprs1801673
1000 genomesrs1801673
hgdprs1801673
ensemblrs1801673
gopubmedrs1801673
geneviewrs1801673
scholarrs1801673
googlers1801673
pharmgkbrs1801673
gwascentralrs1801673
openSNPrs1801673
23andMers1801673
23andMe allrs1801673
SNP Nexus

SNPshotrs1801673
SNPdbers1801673
MSV3drs1801673
GWAS Ctlgrs1801673
GMAF0.002755
Max Magnitude0
? (A;A) (A;T) (T;T) 28

This SNP, a variant in the ATM gene, is 1 of 25 SNPs reported to represent independently minor, but cumulatively significant, increased risk for breast cancer. [PMID 17341484]

For details of all 25 SNPs in this group, along with the two methods used to calculate overall risk estimates for breast cancer, refer to the SNPedia breast cancer entry.

For this particular SNP, the risk (minor) allele is (T).


[PMID 18701470OA-icon.png] Variants in the ATM gene associated with a reduced risk of contralateral breast cancer.


[PMID 19348699OA-icon.png] Variants in the ATM gene and breast cancer susceptibility.


ClinVar
Risk rs1801673(T;T)
Alt rs1801673(T;T)
Reference rs1801673(A;A)
Significance Probable-non-pathogenic
Disease not specified Ataxia-telangiectasia syndrome Hereditary cancer-predisposing syndrome
Variation info
Gene ATM
CLNDBN not specified Ataxia-telangiectasia syndrome Hereditary cancer-predisposing syndrome
Reversed 0
HGVS NC_000011.9:g.108175463A>T
CLNSRC Ambry Genetics ClinVar GeneDx
CLNACC RCV000120145.1, RCV000122859.4, RCV000128902.4,