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rs180177099

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(-;-) 7 Fanconi anemia, complementation group N
(-;GA) 3 increased risk of breast cancer
(GA;GA) 0 common in clinvar
ReferenceGRCh38 38.1/141
Chromosome16
Position23635489
GenePALB2
is asnp
is mentioned by
dbSNPrs180177099
ebirs180177099
HLIrs180177099
Exacrs180177099
Varsomers180177099
Maprs180177099
PheGenIrs180177099
hapmaprs180177099
1000 genomesrs180177099
hgdprs180177099
ensemblrs180177099
gopubmedrs180177099
geneviewrs180177099
scholarrs180177099
googlers180177099
pharmgkbrs180177099
gwascentralrs180177099
openSNPrs180177099
23andMers180177099
23andMe allrs180177099
SNP Nexus

SNPshotrs180177099
SNPdbers180177099
MSV3drs180177099
GWAS Ctlgrs180177099
Max Magnitude7
ClinVar
Risk rs180177099(;)
Alt rs180177099(;)
Reference rs180177099(GA;GA)
Significance Pathogenic
Disease Familial cancer of breast Hereditary cancer-predisposing syndrome
Variation info
Gene PALB2
CLNDBN Familial cancer of breast Hereditary cancer-predisposing syndrome
Reversed 1
HGVS NC_000016.9:g.23646810_23646811delTC
CLNSRC PALB2 database
CLNACC RCV000114457.3, RCV000165605.1,


[PMID 17200668OA-icon.png] PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene.


[PMID 18302019] Analysis of FANCB and FANCN/PALB2 fanconi anemia genes in BRCA1/2-negative Spanish breast cancer families.