|(A;A)||0||common in clinvar|
[PMID 19515749] Favorable impact of the interleukin-4 receptor allelic variant I75 on the survival of diffuse large B-cell lymphoma patients demonstrated in a large prospective clinical trial
[PMID 19796199] Polymorphisms in IL13 pathway genes in asthma and chronic obstructive pulmonary disease
[PMID 22119518] Interleukin-4 receptor alpha polymorphisms in autoimmune myasthenia gravis in a Caucasian population
|Disease||Atopy Acquired immunodeficiency syndrome|
|CLNDBN||Atopy, resistance to Acquired immunodeficiency syndrome, slow progression to|
|CLNSRC||OMIM Allelic Variant|
[PMID 15660293] No evidence of association or interaction between the IL4RA, IL4, and IL13 genes in type 1 diabetes.
[PMID 15726497] Gene-environment interaction effects on the development of immune responses in the 1st year of life.
[PMID 17303794] Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma.
[PMID 17705862] Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples.
[PMID 18625055] Lack of association or interactions between the IL-4, IL-4Ralpha and IL-13 genes, and rheumatoid arthritis.
[PMID 18781131] Interleukin and interleukin receptor gene polymorphisms and susceptibility to melanoma.
[PMID 19131662] A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
[PMID 19330901] Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study.
[PMID 19559392] A candidate gene association study of 77 polymorphisms in migraine.
[PMID 19759553] Genetic and environmental risk factors for childhood eczema development and allergic sensitization in the CCAAPS cohort.
[PMID 19956098] Association analysis of SNPs in the IL4R locus with type I diabetes.
[PMID 19956101] Overview of the Rapid Response data.
[PMID 19956109] The Type I Diabetes Genetics Consortium 'Rapid Response' family-based candidate gene study: strategy, genes selection, and main outcome.
[PMID 20298583] Association of IL-4RA single nucleotide polymorphisms, HLA-DR and HLA-DQ in children with Alternaria-sensitive moderate-severe asthma.
[PMID 20811626] Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.
[PMID 22376040] Gene-gene interactions between candidate gene polymorphisms are associated with total IgE levels in Korean children with asthma.
|qualified_impact||Insufficiently evaluated not reviewed|
[PMID 23299779] Interleukin-10 gene polymorphisms are associated with freedom from treatment failure for patients with Hodgkin lymphoma
[PMID 23924473] Association between the polymorphisms of interleukin-4, the interleukin-4 receptor gene and asthma
[PMID 22484276] Effects of cytokine and cytokine receptor gene variation on high anti-HB titers: following up on Taiwan's neonatal hepatitis B immunization program.
[PMID 24782180] Increased Th17 Cell Frequency and Poor Clinical Outcome in Rheumatoid Arthritis Are Associated With a Genetic Variant in the IL4R Gene, rs1805010
[PMID 25785117] Associations between polymorphisms in the IL-4 and IL-4 receptor genes and urinary carcinomas: a meta-analysis
[PMID 26426602] Polymorphisms in the interleukin 4, interleukin 4 receptor and interleukin 13 genes and allergic phenotype: A case control study