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rs1805762

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) >1.23x risk for hypertension
(C;G) 1.23x risk for hypertension
(G;G) average
ReferenceGRCh38 38.1/141
Chromosome12
Position8945306
GeneM6PR
is asnp
is mentioned by
dbSNPrs1805762
ebirs1805762
HLIrs1805762
Exacrs1805762
Varsomers1805762
Maprs1805762
PheGenIrs1805762
hapmaprs1805762
1000 genomesrs1805762
hgdprs1805762
ensemblrs1805762
gopubmedrs1805762
geneviewrs1805762
scholarrs1805762
googlers1805762
pharmgkbrs1805762
gwascentralrs1805762
openSNPrs1805762
23andMers1805762
23andMe allrs1805762
SNP Nexus

SNPshotrs1805762
SNPdbers1805762
MSV3drs1805762
GWAS Ctlgrs1805762
GMAF0.09963
Max Magnitude
? (C;C) (C;G) (G;G) 28
rs1805762, a SNP in the M6PR gene, was associated with risk for hypertension in a study involving 1,500+ Japanese patients. The odds ratio associated with the risk allele, in dbSNP orientation, rs1805762(G), which is also the most common allele, is 1.23 (CI: 1.10 - 1.37, p = 0.0003). [PMID 18003638]

A SNP in close linkage, rs1805740, has also been reported in association with hypertension risk in the large 2007 study reported by the Wellcome Trust Consortium. [PMID 17554300OA-icon.png]