rs1828591
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common/normal |
| (A;G) | 1.5 | Reduced risk (0.77x) of chronic obstructive pulmonary disease (COPD) |
| (G;G) | 2 | Reduced risk (0.54x) for chronic pulmonary obstructive disease (COPD) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 144559628 |
| Gene | LOC105377462 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1828591 |
| dbSNP (classic) | rs1828591 |
| ClinGen | rs1828591 |
| ebi | rs1828591 |
| HLI | rs1828591 |
| Exac | rs1828591 |
| Gnomad | rs1828591 |
| Varsome | rs1828591 |
| LitVar | rs1828591 |
| Map | rs1828591 |
| PheGenI | rs1828591 |
| Biobank | rs1828591 |
| 1000 genomes | rs1828591 |
| hgdp | rs1828591 |
| ensembl | rs1828591 |
| geneview | rs1828591 |
| scholar | rs1828591 |
| rs1828591 | |
| pharmgkb | rs1828591 |
| gwascentral | rs1828591 |
| openSNP | rs1828591 |
| 23andMe | rs1828591 |
| SNPshot | rs1828591 |
| SNPdbe | rs1828591 |
| MSV3d | rs1828591 |
| GWAS Ctlg | rs1828591 |
| GMAF | 0.388 |
| Max Magnitude | 2 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
| This SNP has been recognized by the Coriell Personalized Medicine Collaborative ICOB.
|
| GWAS snp | |
|---|---|
| PMID | [PMID 19300482 ]
|
| Trait | Chronic Obstructive Pulmonary Disease |
| Title | A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci |
| Risk Allele | |
| P-val | 1E-7 |
| Odds Ratio | 1.38 [1.17-1.63] |
[PMID 19300500] A genome-wide association study of pulmonary function measures in the Framingham Heart Study.
[PMID 19996190] Hedgehog-interacting protein is a COPD susceptibility gene: the Rotterdam Study.
[PMID 23886569] Transient early wheeze and lung function in early childhood associated with chronic obstructive pulmonary disease genes
[PMID 23936167] Refining Susceptibility Loci of Chronic Obstructive Pulmonary Disease with Lung eqtls
[PMID 25073350] [Genetic aspects of occupational chronic obstructive lung disease under exposure to various risk factors]
[PMID 28939338] Comparison of the role of HHIP SNPs in susceptibility to chronic obstructive pulmonary disease between Chinese Han and Mongolian populations.
