|?|| (C;C) (C;T) (T;T) ||28|
nature The inheritance of the AC haplotype of rs1861972 – rs1861973, the C allele of rs1811399, and the C allele of rs1234747 may contribute to autism by affecting microRNA
[PMID 18424904] rs1861972(A) + rs1861973(C) haplotype assoc. with protective effect against autism in a study of 818 Han Chinese (184 diag. autistics, 225 unrelated volunteers, 409 randomly selected)
|Desc||AUTISM, SUSCEPTIBILITY TO, 10; AUTS10|
] Intronic single nucleotide polymorphisms of engrailed homeobox 2 modulate the disease vulnerability of autism in a han chinese population
] Association of the homeobox transcription factor, ENGRAILED 2, 3, with autism spectrum disorder.
[PMID 16252243] Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locus.
[PMID 17948901] Association of the ENGRAILED 2 (EN2) gene with autism in Chinese Han population.
[PMID 19615670] Autism-associated haplotype affects the regulation of the homeobox gene, ENGRAILED 2.
[PMID 20050924] Family-based studies indicate association of Engrailed 2 gene with autism in an Indian population.
[PMID 22180456] Cut-like homeobox 1 and nuclear factor I/B mediate ENGRAILED2 autism spectrum disorder-associated haplotype function.