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rs1864163

From SNPedia

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Stabilizedplus
Geno Mag Summary
(A;G) 2 associated with higher HDL cholesterol
(G;G) 2 associated with higher HDL cholesterol


Make rs1864163(A;A)
ReferenceGRCh38 38.1/141
Chromosome16
Position56963321
GeneCETP
is asnp
is mentioned by
dbSNPrs1864163
ebirs1864163
HLIrs1864163
Exacrs1864163
Varsomers1864163
Maprs1864163
PheGenIrs1864163
hapmaprs1864163
1000 genomesrs1864163
hgdprs1864163
ensemblrs1864163
gopubmedrs1864163
geneviewrs1864163
scholarrs1864163
googlers1864163
pharmgkbrs1864163
gwascentralrs1864163
openSNPrs1864163
23andMers1864163
23andMe allrs1864163
SNP Nexus

SNPshotrs1864163
SNPdbers1864163
MSV3drs1864163
GWAS Ctlgrs1864163
GMAF0.2346
Max Magnitude2
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 18193043]
Trait HDL cholesterol
Title Newly identified loci that influence lipid concentrations and risk of coronary artery disease
Risk Allele G
P-val 7E-39
Odds Ratio 4.12 [NR] mg/dl higher

G allele is associated with 4.12mg/dl increase in HDL cholesterol (good cholesterol). [PMID 18193043]


[PMID 21738485OA-icon.png] Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study


[PMID 20031564OA-icon.png] Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.


GET Evidence
rs1864163
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.25
summary



GWAS snp
PMID [PMID 23455636OA-icon.png]
Trait Age-related macular degeneration
Title Seven new loci associated with age-related macular degeneration.
Risk Allele G
P-val 7E-16
Odds Ratio 1.22 [1.17-1.27]


[PMID 24283500OA-icon.png] CETP gene polymorphisms and risk of coronary atherosclerosis in a Chinese population

GWAS snp
PMID [PMID 19936222OA-icon.png]
Trait Lipid metabolism phenotypes
Title Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
Risk Allele
P-val 7E-22
Odds Ratio 30.38 [NR] unit decrease