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rs1870377

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 0 common in clinvar
Make rs1870377(A;A)
Make rs1870377(A;T)
ReferenceGRCh38 38.1/141
Chromosome4
Position55106807
GeneKDR
is asnp
is mentioned by
dbSNPrs1870377
ebirs1870377
HLIrs1870377
Exacrs1870377
Varsomers1870377
Maprs1870377
PheGenIrs1870377
hapmaprs1870377
1000 genomesrs1870377
hgdprs1870377
ensemblrs1870377
gopubmedrs1870377
geneviewrs1870377
scholarrs1870377
googlers1870377
pharmgkbrs1870377
gwascentralrs1870377
openSNPrs1870377
23andMers1870377
23andMe allrs1870377
SNP Nexus

SNPshotrs1870377
SNPdbers1870377
MSV3drs1870377
GWAS Ctlgrs1870377
GMAF0.2346
Max Magnitude0
? (A;A) (A;T) (T;T) 28

[PMID 19875757] Clinical relevance of vascular endothelial growth factor (VEGFA) and VEGF receptor (VEGFR2) gene polymorphism on the treatment outcome following imatinib therapy


[PMID 22015057] Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study


[PMID 22129133] VEGFA and VEGFR2 genetic polymorphisms and survival in patients with diffuse large B cell lymphoma


[PMID 22507619] Association and interaction between dietary pattern and VEGF receptor-2 (VEGFR2) gene polymorphisms on blood lipids in Chinese Malaysian and Japanese adults

[PMID 18194558OA-icon.png] A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples.

[PMID 20019880OA-icon.png] Polymorphisms in the VEGFA and VEGFR-2 genes and neovascular age-related macular degeneration.

[PMID 20215856OA-icon.png] Genetic association of angiogenesis- and hypoxia-related gene polymorphisms with osteonecrosis of the femoral head.

[PMID 20389299OA-icon.png] Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism.

[PMID 21257617] Association of polymorphisms/haplotypes of the genes encoding vascular endothelial growth factor and its KDR receptor with recurrent pregnancy loss.


GET Evidence
KDR-Q472H
aa_change Gln472His
aa_change_short Q472H
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.19288
summary



[PMID 23111153] Implication of VEGFR2 in systemic lupus erythematosus: a combined genetic and structural biological approach


[PMID 23566851] Association study between of Tie2/angiopoietin-2 and VEGF/KDR pathway gene polymorphisms and vascular malformations


[PMID 25123269] Genetic variants in the KDR gene is associated with the prognosis of transarterial chemoembolization treated hepatocellular carcinoma


ClinVar
Risk rs1870377(A;A)
Alt rs1870377(A;A)
Reference rs1870377(T;T)
Significance Untested
Disease not specified
Variation info
Gene KDR
CLNDBN not specified
Reversed 0
HGVS NC_000004.11:g.55972974T>A
CLNSRC ClinVar
CLNACC RCV000121293.1,



[PMID 26081139] Genetic Variations of Kinase Inserts Domain Receptor (KDR) Gene Are Associated with the Risk of Astrocytomas


[PMID 26254278OA-icon.png] Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy


[PMID 25182707] The relationship of kinase insert domain receptor gene polymorphisms and clinical outcome in advanced hepatocellular carcinoma patients treated with sorafenib


[PMID 27141535] Association of kinase insert domain-containing receptor (KDR) gene polymorphism/ haplotypes with recurrent spontaneous abortion and genetic structure.