|| common in clinvar
] The G allele at the rs1876828 SNP was associated with lower z scores (P = .02) in males but tended to have the opposite association in females (P = .09). CRHR1 polymorphisms may impact the risk of bone density deficits in patients treated with corticosteroids and antimetabolites in a sex-specific manner.
[PMID 15365580] Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans.
[PMID 19750552] Risk and resilience: genetic and environmental influences on development of the stress response.
[PMID 21172166] Pharmacogenetics of antidepressant response.
[PMID 22641026] Predicting inhaled corticosteroid response in asthma with two associated SNPs.
|| Insufficiently evaluated pharmacogenetic
[PMID 23726670] Association of glucocorticoid and type 1 corticotropin-releasing hormone receptors gene variants and risk for depression during pregnancy and post-partum