rs1883832
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (T;T) | 0 | common in clinvar |
| Make rs1883832(C;C) |
| Make rs1883832(C;T) |
| Reference | GRCh38.p2 38.2/146 |
| Chromosome | 20 |
| Position | 46118343 |
| Gene | CD40 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1883832 |
| dbSNP (classic) | rs1883832 |
| ClinGen | rs1883832 |
| ebi | rs1883832 |
| HLI | rs1883832 |
| Exac | rs1883832 |
| Gnomad | rs1883832 |
| Varsome | rs1883832 |
| LitVar | rs1883832 |
| Map | rs1883832 |
| PheGenI | rs1883832 |
| Biobank | rs1883832 |
| 1000 genomes | rs1883832 |
| hgdp | rs1883832 |
| ensembl | rs1883832 |
| geneview | rs1883832 |
| scholar | rs1883832 |
| rs1883832 | |
| pharmgkb | rs1883832 |
| gwascentral | rs1883832 |
| openSNP | rs1883832 |
| 23andMe | rs1883832 |
| SNPshot | rs1883832 |
| SNPdbe | rs1883832 |
| MSV3d | rs1883832 |
| GWAS Ctlg | rs1883832 |
| GMAF | 0.2429 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 18097708] Women with the TT genotype in rs1883832 had increased risk of osteopenia or osteoporosis.
[PMID 18287517
] rs1883832(T;T) influence lymphoma [odds ratio (OR)=1.6, 95% confidence interval (CI)=1.1-2.4]
[PMID 20473910] A functional TNFRSF5 polymorphism and risk of non-Hodgkin lymphoma, a pooled analysis
[PMID 20504251] CD40-1C>T polymorphism (rs1883832) is associated with brain vessel reocclusion after fibrinolysis in ischemic stroke
[PMID 20634952] CD40: Novel Association with Crohn's Disease and Replication in Multiple Sclerosis Susceptibility
[PMID 20682661] Influence of CD40 rs1883832 Polymorphism in Susceptibility to and Clinical Manifestations of Biopsy-proven Giant Cell Arteritis
[PMID 22087016] CD40 gene polymorphisms confer risk of Behcet's disease but not of Vogt-Koyanagi-Harada syndrome in a Han Chinese population
[PMID 22302395] Influence of MIF, CD40, and CD226 polymorphisms on risk of rheumatoid arthritis
[PMID 18045485] The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes.
[PMID 18591382] A novel polymorphism of the human CD40 receptor with enhanced function.
[PMID 18794853] Common variants at CD40 and other loci confer risk of rheumatoid arthritis.
[PMID 19159017] STAT2*C related genotypes and allele but not TLR4 and CD40 gene polymorphisms are associated with higher susceptibility for asthma.
[PMID 20577873] Gene-gene interaction between CD40 and CD40L reduces bone mineral density and increases osteoporosis risk in women.
[PMID 21091218] The CD40 gene polymorphism rs1883832 is associated with risk of acute coronary syndrome in a Chinese case-control study.
[PMID 22077624] A CD40 single-nucleotide polymorphism affects the lymphocyte profiles in the bronchoalveolar lavage of Japanese patients with sarcoidosis.
[PMID 23166616] Study of Association of CD40-CD154 Gene Polymorphisms with Disease Susceptibility and Cardiovascular Risk in Spanish Rheumatoid Arthritis Patients
[PMID 23256180] Association of genetic polymorphisms in CD40 with susceptibility to SLE in the Korean population
[PMID 23613777] Association of SNPs of CD40 gene with multiple sclerosis in Russians.
[PMID 24828072] The SNP rs1883832 in CD40 Gene and Risk of Atherosclerosis in Chinese Population: A Meta-Analysis
[PMID 25305459] Lack of association between CD40 polymorphisms and acute rejection in German liver transplant recipients
[PMID 25373542] Associations of rs4810485 and rs1883832 polymorphisms of CD40 gene with susceptibility and clinical findings of Behçet's disease
[PMID 25802187] Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B
[PMID 26474561] The association of CD40 polymorphisms with CD40 serum levels and risk of systemic lupus erythematosus
[PMID 26545336] The Role of CD40 and CD40L in Bone Mineral Density and in Osteoporosis Risk: A genetic and functional study
[PMID 26823861] CD40 -1C>T polymorphism and the risk of lung cancer in a Chinese population.
[PMID 26957242] [Association of SNP of leukocyte differentiation antigen-CD40 gene and its serum level with ischemic stroke].
[PMID 28590502] A SNP in 5' untranslated region of CD40 gene is associated with an increased risk of ischemic stroke in a Chinese population: a case-control study.
[PMID 28678751] Association between CD40 rs1883832 and immune-related diseases susceptibility: a meta-analysis.
| ClinVar | |
|---|---|
| Risk | rs1883832(C;C) |
| Alt | rs1883832(C;C) |
| Reference | Rs1883832(T;T) |
| Significance | Non-pathogenic |
| Disease | Immunodeficiency with Hyper-IgM not specified |
| Variation | info |
| Gene | CD40 |
| CLNDBN | Immunodeficiency with Hyper-IgM not specified |
| Reversed | 0 |
| HGVS | NC_000020.10:g.44746982T>C |
| CLNSRC | |
| CLNACC | RCV000348388.1, RCV000456068.1, |
[PMID 29254239] Association between CD40 rs1883832 and immune-related diseases susceptibility: A meta-analysis.
[PMID 29780830] The CD40 rs1883832 Polymorphism Affects Sepsis Susceptibility and sCD40L Levels.
[PMID 30223781] Correlation between CTLA-4 and CD40 gene polymorphisms and their interaction in graves' disease in a Chinese Han population.
[PMID 30374748] The association of CD40 polymorphism (rs1883832C/T) and soluble CD40 with the risk of systemic lupus erythematosus among Egyptian patients.
[PMID 31373353] Functional association of a CD40 gene single nucleotide polymorphism with the pathogenesis of coronary heart disease.
[PMID 31183392] Analysis of Genetic Variation in CD40 and CD40L: Relationship with mRNA Relative Expression and Soluble Proteins in Acute Coronary Syndrome.
[PMID 32018016] Impact of CD40 gene polymorphisms on the risk of immune thrombocytopenic purpura.
