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rs1885120

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0
Make rs1885120(C;C)
Make rs1885120(C;G)
ReferenceGRCh38 38.1/141
Chromosome20
Position34989186
GeneMIR499A, MYH7B
is asnp
is mentioned by
dbSNPrs1885120
ebirs1885120
HLIrs1885120
Exacrs1885120
Varsomers1885120
Maprs1885120
PheGenIrs1885120
hapmaprs1885120
1000 genomesrs1885120
hgdprs1885120
ensemblrs1885120
gopubmedrs1885120
geneviewrs1885120
scholarrs1885120
googlers1885120
pharmgkbrs1885120
gwascentralrs1885120
openSNPrs1885120
23andMers1885120
23andMe allrs1885120
SNP Nexus

SNPshotrs1885120
SNPdbers1885120
MSV3drs1885120
GWAS Ctlgrs1885120
GMAF0.01974
Max Magnitude0
? (C;C) (C;G) (G;G) 28
[PMID 18488026OA-icon.png] 2,019 cases and 2,105 controls. Using pooling, we identified a new melanoma risk locus on chromosome 20 (rs910873 and rs1885120 combined P less than 1 10-15. The per allele odds ratio was 1.75 (1.53, 2.01), with evidence for stronger association in early-onset cases.
OMIM612263
DescMELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 7; CMM7
Variant
Relatedalso
[PMID 21221757OA-icon.png] ASIP genetic variants and the number of non-melanoma skin cancers


[PMID 19578364OA-icon.png] Genome-wide association study identifies three loci associated with melanoma risk.


[PMID 19995372OA-icon.png] Melanoma susceptibility variants on chromosome 20q11.22 are associated with pigmentary traits and the risk of nonmelanoma skin cancer.


[PMID 20224305] Modest association of malignant melanoma with the rs910873 and rs1885120 markers on chromosome 20: a population-based study.


GET Evidence
rs1885120
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.984375
summary may be associated with cutaneous melanoma



[PMID 23393597OA-icon.png] Replication and Predictive Value of SNPs Associated with Melanoma and Pigmentation Traits in a Southern European Case-Control Study