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rs1927911

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) normal
(C;T) 0.88x lower risk of nonfatal myocardial infarction
(G;G) 0
(T;T) 0.88x lower risk of nonfatal myocardial infarction
ReferenceGRCh38 38.1/141
Chromosome9
Position117707776
GeneTLR4
is asnp
is mentioned by
dbSNPrs1927911
ebirs1927911
HLIrs1927911
Exacrs1927911
Varsomers1927911
Maprs1927911
PheGenIrs1927911
hapmaprs1927911
1000 genomesrs1927911
hgdprs1927911
ensemblrs1927911
gopubmedrs1927911
geneviewrs1927911
scholarrs1927911
googlers1927911
pharmgkbrs1927911
gwascentralrs1927911
openSNPrs1927911
23andMers1927911
23andMe allrs1927911
SNP Nexus

SNPshotrs1927911
SNPdbers1927911
MSV3drs1927911
GWAS Ctlgrs1927911
GMAF0.3857
Max Magnitude0
? (C;C) (C;T) (T;T) 28
The rs1927911(T) allele was associated with a lower risk of nonfatal myocardial infarction (odds ratio 0.88, CI: 0.77 - 0.99) in 848 patients composed of both postmenopausal women and hypertensive men/women.[PMID 18549840OA-icon.png]

[PMID 23936790OA-icon.png] Association of Toll-like receptor 4 polymorphisms with diabetic foot ulcers and application of artificial neural network in DFU risk assessment in type 2 diabetes patients

[PMID 19380025] The association between Toll-like receptor 4 (TLR4) polymorphisms and the risk of prostate cancer in Korean men


[PMID 20685742] Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma


[PMID 21081146] Impact of Toll-like receptor 4 polymorphisms on risk of cancer


[PMID 21921986OA-icon.png] Toll-like receptor 4 gene polymorphisms do not associate with normal tension glaucoma in a Korean population


[PMID 22272615] Common variants in toll-like receptor 4 confer susceptibility to Alzheimer's disease in a Han Chinese population


[PMID 22238472OA-icon.png] Variants in toll-like receptor 1 and 4 genes are associated with Chlamydia trachomatis among women with pelvic inflammatory disease


[PMID 17699831OA-icon.png] Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study.


[PMID 18298826OA-icon.png] Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol.


[PMID 18396467OA-icon.png] Genetic variation and haplotype structures of innate immunity genes in eastern India.


[PMID 18422738OA-icon.png] Study of Toll-like receptor gene loci in sarcoidosis.


[PMID 18586872] Association of Toll-like receptor 4 gene polymorphisms with normal tension glaucoma.


[PMID 19131814OA-icon.png] Variation in the TLR4 gene influences the risk of organ failure and shock posttrauma: a cohort study.


[PMID 19500628] Association analysis of Toll-like receptor 4 polymorphisms with autoimmune pancreatitis.


[PMID 19503741OA-icon.png] Coding variant Met72Thr in the PEDF gene and risk of neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.


[PMID 19567509OA-icon.png] Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes.


[PMID 19586676OA-icon.png] Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection.


[PMID 19753309OA-icon.png] SOD2 gene polymorphisms in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.


[PMID 20011079OA-icon.png] Lack of association between toll-like receptor 4 gene polymorphisms and sarcoidosis-related uveitis in Japan.


[PMID 20200442OA-icon.png] Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.


[PMID 20227302] Polymorphisms in innate immunity genes associated with development of bronchiolitis obliterans after lung transplantation.


[PMID 20463618OA-icon.png] Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.


[PMID 21403649] Association of polymorphisms in the TLR4 gene with the risk of developing neutropenia in children with leukemia.


[PMID 23084080] The TLR4 gene polymorphisms and susceptibility to cancer: A systematic review and meta-analysis


[PMID 23639307] Childhood allergic rhinitis, traffic-related air pollution, and variability in the GSTP1, TNF, TLR2, and TLR4 genes: results from the TAG Study


[PMID 24365597] Polymorphisms of the TLR4 gene and risk of gastric cancer


[PMID 22525209] Common polymorphisms in TLR4 gene associated with susceptibility to pulmonary tuberculosis in the Sudanese.


[PMID 22831837] Association of Toll-like receptor 4 gene polymorphisms in Japanese subjects with primary open-angle, normal-tension, and exfoliation glaucoma.


[PMID 24929142] Genetic polymorphisms in the Toll-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer


[PMID 25216863] Association between Toll-like receptor 4 and interleukin 17 gene polymorphisms and colorectal cancer susceptibility in Northeast China


[PMID 25590839OA-icon.png] TLR4 rs1927911, but Not TLR2 rs5743708, Is Associated With Atherosclerotic Cerebral Infarction in the Southern Han Population: A Case-Control Study


[PMID 25840711OA-icon.png] Interactions between innate immunity genes and early-life risk factors in allergic rhinitis


[PMID 25908385] Association of TLR4 gene polymorphisms with sporadic Parkinson's disease in a Han Chinese population


[PMID 25947554] The association between toll-like receptor 4 polymorphisms and diabetic retinopathy in Chinese patients with type 2 diabetes


[PMID 25360682OA-icon.png] Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis