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rs2011077

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 1 Normal risk of developing prostate cancer, BPH, and metastatic prostate cancer
(A;G) In Japanese, 2.4x risk of prostate cancer, 1.7x increased risk of BPH, and 1.5x increased risk of developing metastatic prostate cancer
(G;G) 3 In Japanese, 6.2x increased risk of developing prostate cancer, a 3x increased risk of developing BPH, and a 5.5x increased risk of developing metastatic prostate cancer
ReferenceGRCh38 38.1/142
Chromosome5
Position177094455
GeneFGFR4
is asnp
is mentioned by
dbSNPrs2011077
ebirs2011077
HLIrs2011077
Exacrs2011077
Varsomers2011077
Maprs2011077
PheGenIrs2011077
hapmaprs2011077
1000 genomesrs2011077
hgdprs2011077
ensemblrs2011077
gopubmedrs2011077
geneviewrs2011077
scholarrs2011077
googlers2011077
pharmgkbrs2011077
gwascentralrs2011077
openSNPrs2011077
23andMers2011077
23andMe allrs2011077
SNP Nexus

SNPshotrs2011077
SNPdbers2011077
MSV3drs2011077
GWAS Ctlgrs2011077
GMAF0.2493
Max Magnitude3
? (A;A) (A;G) (G;G) 28

A study of ~500 Japanese prostate cancer patients found that individuals with a rs2011077(G;G) genotype had a 6.2- and 3-fold increased risk of prostate cancer and benign prostate hyperplasia (BPH), and a 5.5-fold increased risk of metastatic prostate cancer, compared to the (A;A) genotype.[PMID 18756523]