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rs2016520

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0
Make rs2016520(A;G)
Make rs2016520(G;G)
ReferenceGRCh38 38.1/142
Chromosome6
Position35411001
GenePPARD
is asnp
is mentioned by
dbSNPrs2016520
ebirs2016520
HLIrs2016520
Exacrs2016520
Varsomers2016520
Maprs2016520
PheGenIrs2016520
hapmaprs2016520
1000 genomesrs2016520
hgdprs2016520
ensemblrs2016520
gopubmedrs2016520
geneviewrs2016520
scholarrs2016520
googlers2016520
pharmgkbrs2016520
gwascentralrs2016520
openSNPrs2016520
23andMers2016520
23andMe allrs2016520
SNP Nexus

SNPshotrs2016520
SNPdbers2016520
MSV3drs2016520
GWAS Ctlgrs2016520
GMAF0.2314
Max Magnitude0
? (A;A) (A;G) (G;G) 28

Associated with baseline cholesterol levels in a study of 9,000+ individuals in Washington County, Maryland.[PMID 18288282OA-icon.png]

Neighborrs2267668
Distance856


[PMID 19383774] A single nucleotide polymorphism on exon-4 of the gene encoding PPAR{delta} is associated with reduced height in adults and children



[PMID 19653005] The combined impact of metabolic gene polymorphisms on elite endurance athlete status and related phenotypes


[PMID 22192471OA-icon.png] The peroxisome proliferator-activated receptor delta +294T > C polymorphism and alcohol consumption on serum lipid levels


[PMID 16979821] PPARD haplotype influences cholesterol metabolism but is no risk factor of Alzheimer's disease.


[PMID 18375961OA-icon.png] Polymorphism of genes related to insulin sensitivity and the risk of biliary tract cancer and biliary stone: a population-based case-control study in Shanghai, China.


[PMID 18657264OA-icon.png] Interaction between Calpain 5, Peroxisome proliferator-activated receptor-gamma and Peroxisome proliferator-activated receptor-delta genes: a polygenic approach to obesity.


[PMID 18676870OA-icon.png] Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.


[PMID 19666693] Is there an interaction between PPARD T294C and PPARGC1A Gly482Ser polymorphisms and human endurance performance?


[PMID 20200337] Peroxisome proliferator-activated receptor-delta genotype influences metabolic phenotype and may influence lipid response to statin therapy in humans: a genetics of diabetes audit and research Tayside study.


[PMID 20808897OA-icon.png] Disease-associated mutations that alter the RNA structural ensemble.


[PMID 20811626OA-icon.png] Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.


[PMID 21487230] Effects of peroxisome proliferator-activated receptors, dietary fat intakes and gene-diet interactions on peak particle diameters of low-density lipoproteins.


[PMID 22968028] [Association of both peroxisome proliferator-activated receptor, gene-gene interactions and the body mass index]


GET Evidence
rs2016520
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.679688
summary



[PMID 23545576OA-icon.png] Association of peroxisome proliferator-activated receptor α/δ/γ with obesity, and gene-gene interaction, in the Chinese Han population


[PMID 23906684] Genetic associations with coronary heart disease: Meta-analyses of 12 candidate genetic variants


[PMID 23937834] [Effects related to gene-gene interactions of peroxisome proliferator-activated receptor on essential hypertension]


[PMID 23363867] [Gene-gene interactions among the peroxisome proliferator-activated receptor polymorphisms for hypertriglyceridemia]


[PMID 23355348] Interactions of several single nucleotide polymorphisms and high body mass index on serum lipid traits.


[PMID 26110145OA-icon.png] Gene-Gene Interactions among Pparα/δ/γ Polymorphisms for Apolipoprotein (Apo) A-I/Apob Ratio in Chinese Han Population


[PMID 26268872] [Association and interaction between 10 SNP of peroxisome proliferator-activated receptor and non-HDL-C]


[PMID 24599720] Effect of obesity on the association between common variations in the PPAR gene and C-reactive protein level in Chinese Han population


[PMID 26613934] Case-control study on association of peroxisome proliferator-activated receptor-δ and SNP-SNP interactions with essential hypertension in Chinese Han population.