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rs2031920

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 normal
(C;T) carrier of one CYP2E1_-1055C>T allele
(T;T) CYP2E1_-1055C>T homozygote
ReferenceGRCh38 38.1/142
Chromosome10
Position133526341
GeneCYP2E1
is asnp
is mentioned by
dbSNPrs2031920
ebirs2031920
HLIrs2031920
Exacrs2031920
Varsomers2031920
Maprs2031920
PheGenIrs2031920
hapmaprs2031920
1000 genomesrs2031920
hgdprs2031920
ensemblrs2031920
gopubmedrs2031920
geneviewrs2031920
scholarrs2031920
googlers2031920
pharmgkbrs2031920
gwascentralrs2031920
openSNPrs2031920
23andMers2031920
23andMe allrs2031920
SNP Nexus

SNPshotrs2031920
SNPdbers2031920
MSV3drs2031920
GWAS Ctlgrs2031920
GMAF0.08953
Max Magnitude0
? (C;C) (C;T) (T;T) 28
rs2031920 is a SNP in the CYP2E1 gene.

The rs2031920(T) allele defines the CYP2E1_-1055C>T variant.


[PMID 20663217OA-icon.png] Genetic Polymorphisms of CYP2E1, GSTP1, NQO1 and MPO and the Risk of Nasopharyngeal Carcinoma in a Han Chinese Population of Southern China

OMIM124040
DescCYTOCHROME P450, SUBFAMILY IIE; CYP2E1
Variant
Relatedalso
OMIM124040
Desc
Variant0001
Relatedalso


[PMID 22126492] Genetic Polymorphisms of the CYP2E1 Gene do not Contribute to Oral Cancer Susceptibility in South Indians


[PMID 22761909OA-icon.png] Synergistic Association of PTGS2 and CYP2E1 Genetic Polymorphisms with Lung Cancer Risk in Northeastern Chinese


[PMID 22815852OA-icon.png] Systematic Functional Characterization of Cytochrome P450 2E1 Promoter Variants in the Chinese Han Population


[PMID 15576619OA-icon.png] Hematotoxicity in workers exposed to low levels of benzene.


[PMID 17380320] Genotype and allele frequencies of polymorphic CYP2E1 in the Turkish population.


[PMID 17885617] Genetic polymorphisms and benzene metabolism in humans exposed to a wide range of air concentrations.


[PMID 17903301OA-icon.png] Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study.


[PMID 18663376OA-icon.png] Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene.


[PMID 18936436OA-icon.png] Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.


[PMID 18992148OA-icon.png] Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.


[PMID 19390575OA-icon.png] Lung cancer susceptibility model based on age, family history and genetic variants.


[PMID 19537956OA-icon.png] CYP1A1 genotype modifies the impact of smoking on effectiveness of HAART among women.


[PMID 20082485OA-icon.png] Genetic variants involved in gallstone formation and capsaicin metabolism, and the risk of gallbladder cancer in Chilean women.


[PMID 20675267OA-icon.png] Polymorphisms in GSTT1, GSTZ1, and CYP2E1, disinfection by-products, and risk of bladder cancer in Spain.


[PMID 21741876] Polymorphisms in tobacco metabolism and DNA repair genes modulate oral precancer and cancer risk.


[PMID 22200898] Maternal smoking during pregnancy, genetic polymorphisms of metabolic enzymes, and childhood acute leukemia: the ESCALE study (SFCE).


[PMID 23595220] Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis


[PMID 23460870OA-icon.png] Cytochrome P450 2E1 gene polymorphisms/haplotypes and anti-tuberculosis drug-induced hepatitis in a Chinese cohort


[PMID 24288753] CYP2E1 Gene Promoter Polymorphism -1293G>C Increases the Risk of Essential Hypertension in Men with Alcohol Abuse


[PMID 22560290] A comparison of Val81Met and other polymorphisms of alcohol metabolising genes in patients and controls in Northern Spain.


[PMID 23130019OA-icon.png] Frequencies of 23 functionally significant variant alleles related with metabolism of antineoplastic drugs in the chilean population: comparison with caucasian and asian populations.


[PMID 23404349] Childhood acute leukemia, maternal beverage intake during pregnancy, and metabolic polymorphisms.


[PMID 25017831] N-acetyltransferase and cytochrome P450 2E1 gene polymorphisms and susceptibility to antituberculosis drug hepatotoxicity in an Indian population


ClinVar
Risk rs2031920(T;T)
Alt rs2031920(T;T)
Reference rs2031920(C;C)
Significance Other
Disease CYP2E1*5B ALLELE
Variation info
Gene CYP2E1
CLNDBN CYP2E1*5B ALLELE
Reversed 0
HGVS NC_000010.10:g.135339845C>T
CLNSRC ClinVar
CLNACC RCV000018383.24,



[PMID 26373042] Polymorphisms in NEIL-2, APE-1, CYP2E1 and MDM2 Genes are Independent Predictors of Gastric Cancer Risk in a Northern Jiangsu Population (China)


[PMID 26582733] [Genetic polymorphism of cytochrome P450 2E1 and the risk of nasopharyngeal carcinoma]