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rs2032583(T;T)

From SNPedia

7x less likely to respond to certain antidepressants.
Is agenotype
ofrs2032583
GeneABCB1
Chromosome7
Position87,531,245
mentionedby
Magnitude2
ReputeBad
Geno Mag Summary
(C;C) 1.9 7x more likely to respond to certain antidepressants.
(C;T) 1.9 7x more likely to respond to certain antidepressants.
(T;T) 2 7x less likely to respond to certain antidepressants.

This version of a blood brain barrier protein blocks many common antidepressants from entering the brain, including: amitriptyline (Elavil), citalopram (Celexa), paroxetine (Paxil), and venlafaxine (Effexor). That makes those antidepressants 7 times less effective.