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rs2069514

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) CYP1A2*1C homozygote
(A;G) carrier of one CYP1A2*1C allele
(G;G) 0 normal
ReferenceGRCh38 38.1/141
Chromosome15
Position74745879
is asnp
is mentioned by
dbSNPrs2069514
ebirs2069514
HLIrs2069514
Exacrs2069514
Varsomers2069514
Maprs2069514
PheGenIrs2069514
hapmaprs2069514
1000 genomesrs2069514
hgdprs2069514
ensemblrs2069514
gopubmedrs2069514
geneviewrs2069514
scholarrs2069514
googlers2069514
pharmgkbrs2069514
gwascentralrs2069514
openSNPrs2069514
23andMers2069514
23andMe allrs2069514
SNP Nexus

SNPshotrs2069514
SNPdbers2069514
MSV3drs2069514
GWAS Ctlgrs2069514
GMAF0.1873
Max Magnitude0
rs2069514, also known as -3860G>A, is a SNP in the CYP1A2 gene.

The rs2069514(A) allele defines the CYP1A2*1C variant.



[PMID 22141270] [Single nucleotide polymorphisms of CYP1A2 and their correlation with prostate cancer]

[PMID 16864595] The influence of genetic polymorphisms in Ahr, CYP1A1, CYP1A2, CYP1B1, GST M1, GST T1 and UGT1A1 on urine 1-hydroxypyrene glucuronide concentrations in healthy subjects from Rio Grande do Sul, Brazil.


[PMID 18936436OA-icon.png] Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.


GET Evidence
rs2069514
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.179688
summary



[PMID 23128882] Role of CYP1A2 polymorphisms in breast cancer risk in women


[PMID 23462460] Current evidence on the relationship between three polymorphisms in the CYP1A2 gene and the risk of cancer.


[PMID 25081684] Four Polymorphisms in the Cytochrome P450 1A2 (CYP1A2) Gene and Lung Cancer Risk: a Meta-analysis


[PMID 26015935OA-icon.png] CYP1A2 rs2069514 polymorphism and lung cancer susceptibility: a meta-analysis