rs2069827

plus

Geno	Mag	Summary
(G;G)	0

Make rs2069827(G;T)

Make rs2069827(T;T)

Reference

GRCh38 38.1/141

Chromosome

7

Position

22725837

Gene	IL6, LOC541472

is a	snp
is	mentioned by
dbSNP	rs2069827
dbSNP (classic)	rs2069827
ClinGen	rs2069827
ebi	rs2069827
HLI	rs2069827
Exac	rs2069827
Gnomad	rs2069827
Varsome	rs2069827
LitVar	rs2069827
Map	rs2069827
PheGenI	rs2069827
Biobank	rs2069827
1000 genomes	rs2069827
hgdp	rs2069827
ensembl	rs2069827
geneview	rs2069827
scholar	rs2069827
google	rs2069827
pharmgkb	rs2069827
gwascentral	rs2069827
openSNP	rs2069827
23andMe	rs2069827
SNPshot	rs2069827
SNPdbe	rs2069827
MSV3d	rs2069827
GWAS Ctlg	rs2069827

GMAF

0.04775

Max Magnitude

0

?

(G;G) (G;T) (T;T)

28

[PMID 19280716] The IL6-174G/C polymorphism is associated with celiac disease susceptibility in girls.

OMIM	147620
Desc	INTERLEUKIN 6; IL6
Variant
Related	also

[PMID 21889771] Lack of association between IL6 single nucleotide polymorphisms and cardiovascular disease in Spanish patients with rheumatoid arthritis

[PMID 22234866 ] Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity.

[PMID 16644865] Genetic variation in IL6 gene and type 2 diabetes: tagging-SNP haplotype analysis in large-scale case-control study and meta-analysis.

[PMID 17623760] Interleukin-6 genetic variability and adiposity: associations in two prospective cohorts and systematic review in 26,944 individuals.

[PMID 17847004 ] Common variants in the BMP2, BMP4, and HJV genes of the hepcidin regulation pathway modulate HFE hemochromatosis penetrance.

[PMID 18420533 ] The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN studyboxs.

[PMID 18496509 ] An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients.

[PMID 18781131 ] Interleukin and interleukin receptor gene polymorphisms and susceptibility to melanoma.

[PMID 19272152 ] IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study.

[PMID 19359268 ] Associations of IL6 polymorphisms with lung function decline and COPD.

[PMID 19387461 ] Interleukin-6 haplotypes and the response to therapy of chronic hepatitis C virus infection.

[PMID 23027890] Influence of the IL6 gene in susceptibility to systemic sclerosis.

[PMID 23459936 ] Exploring the genetic basis of chronic periodontitis: a genome-wide association study.

[PMID 31082334] [Correlation between interleukin-6 single nucleotide polymorphism and the occurrence and prognosis of hepatitis B virus-associated acute-on-chronic liver failure].