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rs2069830

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs2069830(C;T)
Make rs2069830(T;T)
ReferenceGRCh38 38.1/141
Chromosome7
Position22727518
GeneIL6, MIR632
is asnp
is mentioned by
dbSNPrs2069830
ebirs2069830
HLIrs2069830
Exacrs2069830
Varsomers2069830
Maprs2069830
PheGenIrs2069830
hapmaprs2069830
1000 genomesrs2069830
hgdprs2069830
ensemblrs2069830
gopubmedrs2069830
geneviewrs2069830
scholarrs2069830
googlers2069830
pharmgkbrs2069830
gwascentralrs2069830
openSNPrs2069830
23andMers2069830
23andMe allrs2069830
SNP Nexus

SNPshotrs2069830
SNPdbers2069830
MSV3drs2069830
GWAS Ctlgrs2069830
GMAF0.01837
Max Magnitude0
? (C;C) (C;T) (T;T) 28
[PMID 18727828OA-icon.png] stroke rs2069830(T) (frequency = 5%) protective among non-smokers (OR = 0.30, 95% CI=0.11-.082, p=0.02), but not among smokers (OR = 1.63, 95% CI=0.48-5.58, p=0.43)
Neighborrs1800795
Distance492
Neighborrs2069832
Distance296
[PMID 19387461OA-icon.png] Interleukin-6 haplotypes and the response to therapy of chronic hepatitis C virus infection


[PMID 18496509OA-icon.png] An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients.


[PMID 19267250OA-icon.png] C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and older.


[PMID 19503017OA-icon.png] Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma.


[PMID 19729864OA-icon.png] Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the Cardiovascular Health Study.


GET Evidence
IL6-P32S
aa_change Pro32Ser
aa_change_short P32S
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.026306
summary