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rs2070744(T;T)

From SNPedia

cardiovascular differences
Is agenotype
ofrs2070744
GeneNOS3
Chromosome7
Position150,992,991
mentionedby
Magnitude2.1
ReputeGood
Geno Mag Summary
(C;C) 0.1 increased prostate cancer risk
(C;T) None
(T;T) 2.1 cardiovascular differences

This is found in high frequency male athletes from power sports such as jumpers, throwers, and sprinters. [PMID 19701646]

There may be negative health consequences with increased risk of cardiovascular disorders.[PMID 16979000] and response

Mexicans with this SNP, and also a T at rs1800783, have lower LDL cholesterol.

People with this SNP, and also a T at rs1800783, may be less responsive to hypnosis.[PMID 19853644]

Notably, this SNP does not change the amino acid (it is in the promoter region and doesn't encode the protein's amino acid sequence). The population frequencies in HapMap are incorrect.