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rs2070895

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common in complete genomics
Make rs2070895(A;A)
Make rs2070895(A;G)
ReferenceGRCh38 38.1/141
Chromosome15
Position58431740
GeneLIPC, LOC102724766
is asnp
is mentioned by
dbSNPrs2070895
ebirs2070895
HLIrs2070895
Exacrs2070895
Varsomers2070895
Maprs2070895
PheGenIrs2070895
hapmaprs2070895
1000 genomesrs2070895
hgdprs2070895
ensemblrs2070895
gopubmedrs2070895
geneviewrs2070895
scholarrs2070895
googlers2070895
pharmgkbrs2070895
gwascentralrs2070895
openSNPrs2070895
23andMers2070895
23andMe allrs2070895
SNP Nexus

SNPshotrs2070895
SNPdbers2070895
MSV3drs2070895
GWAS Ctlgrs2070895
GMAF0.3696
Max Magnitude0
? (A;A) (A;G) (G;G) 28
OMIM151670
DescLIPASE, HEPATIC; LIPC
Variant
Relatedalso
OMIM612797
DescHIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS
Variant
Relatedalso
[PMID 20222961OA-icon.png] Association of LIPC -250G>A polymorphism and several environmental factors with serum lipid levels in the Guangxi Bai Ku Yao and Han populations


[PMID 22073289OA-icon.png] Interaction between Cholesteryl Ester Transfer Protein and Hepatic Lipase Encoding Genes and the Risk of Type 2 Diabetes: Results from the Telde Study


[PMID 18364377] The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects.


[PMID 19014573OA-icon.png] Application of two machine learning algorithms to genetic association studies in the presence of covariates.


[PMID 19041386OA-icon.png] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.


[PMID 19060906OA-icon.png] Common variants at 30 loci contribute to polygenic dyslipidemia.


[PMID 19101670OA-icon.png] LIPC variants in the promoter and intron 1 modify HDL-C levels in a sex-specific fashion.


[PMID 20385819OA-icon.png] Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.


[PMID 23355348] Interactions of several single nucleotide polymorphisms and high body mass index on serum lipid traits.

GWAS snp
PMID [PMID 24816252OA-icon.png]
Trait Blood metabolite levels
Title An atlas of genetic influences on human blood metabolites.
Risk Allele A
P-val 1E-18
Odds Ratio .03 [0.024-0.036] unit increase


[PMID 25926410] Dietary Fat Intake Modifies the Effect of a Common Variant in the LIPC Gene on Changes in Serum Lipid Concentrations during a Long-Term Weight-Loss Intervention Trial


[PMID 27656463] The rs2070895 (-250G/A) Single Nucleotide Polymorphism in Hepatic Lipase (HL) Gene and the Risk of Coronary Artery Disease in North Indian Population: A Case-Control Study.