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rs2075252

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0 common in clinvar
Make rs2075252(A;G)
Make rs2075252(G;G)
ReferenceGRCh38 38.1/141
Chromosome2
Position169154475
GeneLRP2
is asnp
is mentioned by
dbSNPrs2075252
ebirs2075252
HLIrs2075252
Exacrs2075252
Varsomers2075252
Maprs2075252
PheGenIrs2075252
hapmaprs2075252
1000 genomesrs2075252
hgdprs2075252
ensemblrs2075252
gopubmedrs2075252
geneviewrs2075252
scholarrs2075252
googlers2075252
pharmgkbrs2075252
gwascentralrs2075252
openSNPrs2075252
23andMers2075252
23andMe allrs2075252
SNP Nexus

SNPshotrs2075252
SNPdbers2075252
MSV3drs2075252
GWAS Ctlgrs2075252
GMAF0.258
Max Magnitude0
? (A;A) (A;G) (G;G) 28
[PMID 18559602OA-icon.png] Association of megalin genetic polymorphisms with prostate cancer risk and prognosis.


[PMID 22170372OA-icon.png] Vitamin D receptor and megalin gene polymorphisms and their associations with longitudinal cognitive change in US adults.


GET Evidence
LRP2-K4094E
aa_change Lys4094Glu
aa_change_short K4094E
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.79894
summary Associated with hearing loss with cisplatin.



[PMID 23274376] Cisplatin-induced ototoxicity in pediatric solid tumors: the role of glutathione S-transferases and megalin genetic polymorphisms


ClinVar
Risk rs2075252(G;G)
Alt rs2075252(G;G)
Reference rs2075252(A;A)
Significance Probable-non-pathogenic
Disease not specified
Variation info
Gene LRP2
CLNDBN not specified
Reversed 1
HGVS NC_000002.11:g.170010985T>C
CLNSRC ClinVar University of Chicago
CLNACC RCV000117508.2,