Have questions? Visit https://www.reddit.com/r/SNPedia

rs2078267

From SNPedia

Orientationminus
Stabilizedminus
Make rs2078267(A;A)
Make rs2078267(A;G)
Make rs2078267(G;G)
ReferenceGRCh38 38.1/141
Chromosome11
Position64566642
GeneSLC22A11
is asnp
is mentioned by
dbSNPrs2078267
ebirs2078267
HLIrs2078267
Exacrs2078267
Varsomers2078267
Maprs2078267
PheGenIrs2078267
hapmaprs2078267
1000 genomesrs2078267
hgdprs2078267
ensemblrs2078267
gopubmedrs2078267
geneviewrs2078267
scholarrs2078267
googlers2078267
pharmgkbrs2078267
gwascentralrs2078267
openSNPrs2078267
23andMers2078267
23andMe allrs2078267
SNP Nexus

SNPshotrs2078267
SNPdbers2078267
MSV3drs2078267
GWAS Ctlgrs2078267
GMAF0.2548
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 20884846OA-icon.png]
Trait
Title Multiple Genetic Loci Influence Serum Urate And Their Relationship With Gout and Cardiovascular Disease Risk Factors
Risk Allele C
P-val 2E-26
Odds Ratio 6.80 [5.55-8.05] umol/l increase


[PMID 16934049OA-icon.png] Torsemide renal clearance and genetic variation in luminal and basolateral organic anion transporters.


[PMID 19503597OA-icon.png] Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.


[PMID 20162742OA-icon.png] Predictive value of 8 genetic loci for serum uric acid concentration.


[PMID 20162743OA-icon.png] Common variants in SLC17A3 gene affect intra-personal variation in serum uric acid levels in longitudinal time series.

GWAS snp
PMID [PMID 23263486OA-icon.png]
Trait Urate levels
Title Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Risk Allele T
P-val 9E-38
Odds Ratio .07 [0.061-0.085] mg/dl decrease


[PMID 24360580OA-icon.png] Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects


[PMID 25867401] Polymorphisms of uric transporter proteins in the pathogenesis of gout in a Chinese Han population