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rs2088885

From SNPedia

Orientationplus
Stabilizedplus
Make rs2088885(A;A)
Make rs2088885(A;C)
Make rs2088885(C;C)
ReferenceGRCh38 38.1/141
Chromosome3
Position171253502
GeneTNIK
is asnp
is mentioned by
dbSNPrs2088885
ebirs2088885
HLIrs2088885
Exacrs2088885
Varsomers2088885
Maprs2088885
PheGenIrs2088885
hapmaprs2088885
1000 genomesrs2088885
hgdprs2088885
ensemblrs2088885
gopubmedrs2088885
geneviewrs2088885
scholarrs2088885
googlers2088885
pharmgkbrs2088885
gwascentralrs2088885
openSNPrs2088885
23andMers2088885
23andMe allrs2088885
SNP Nexus

SNPshotrs2088885
SNPdbers2088885
MSV3drs2088885
GWAS Ctlgrs2088885
GMAF0.4982
Max Magnitude
? (A;A) (A;C) (C;C) 28
GWAS snp
PMID [PMID 19023125OA-icon.png]
Trait Brain imaging in schizophrenia (interaction)
Title A Genome-Wide Association Study of Schizophrenia Using Brain Activation as a Quantitative Phenotype
Risk Allele
P-val 0.000006
Odds Ratio NR NR

[PMID 19023125OA-icon.png] less than 10^-6 p-value interaction with quantitative trait (mean oxygen level-dependent signal in the DLPFC while performing a working memory task [SIRP]) measured (among 64 subjects with schizophrenia and 74 matched controls) - TNIK related to HPA function and enviromental stress response, in the adult it mediates stress related responses and affects LTP in concert with RAPT2



GET Evidence
rs2088885
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.570312
summary