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rs2144908

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;A)
Make rs2144908(A;A)
Make rs2144908(A;G)
Make rs2144908(G;G)
ReferenceGRCh38 38.1/141
Chromosome20
Position44357077
GeneHNF4A
is asnp
is mentioned by
dbSNPrs2144908
ebirs2144908
HLIrs2144908
Exacrs2144908
Varsomers2144908
Maprs2144908
PheGenIrs2144908
hapmaprs2144908
1000 genomesrs2144908
hgdprs2144908
ensemblrs2144908
gopubmedrs2144908
geneviewrs2144908
scholarrs2144908
googlers2144908
pharmgkbrs2144908
gwascentralrs2144908
openSNPrs2144908
23andMers2144908
23andMe allrs2144908
SNP Nexus

SNPshotrs2144908
SNPdbers2144908
MSV3drs2144908
GWAS Ctlgrs2144908
GMAF0.2493
Max Magnitude
? (A;A) (A;G) (G;G) 28
Affects type-2 diabetes

[PMID 15047633] [PMID 15504983] [PMID 15735892] [PMID 16522129] [PMID 16522130] [PMID 16523192] [PMID 16523193] [PMID 16523194] [PMID 16752173]

popular in pubmed


[PMID 21544032] Genetic and clinical risk factors of new-onset diabetes after transplantation in Hispanic kidney transplant recipients


[PMID 21633728] Hepatocyte nuclear factor 4 alpha P2 promoter variants associate with insulin resistance


[PMID 21983932] Association of Hepatocyte Nuclear Factor 4 Alpha Polymorphisms with Type 2 Diabetes With or Without Metabolic Syndrome in Malaysia

[PMID 16186411OA-icon.png] Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians.

[PMID 16838170] Single nucleotide polymorphisms of the HNF4alpha gene are associated with the conversion to type 2 diabetes mellitus: the STOP-NIDDM trial.

[PMID 17805472] Association of genetic variations near P2 promoter of the hepatocyte nuclear factor-4alpha gene and insulin secretion index in Thais.

[PMID 17827402] Studies in 3,523 Norwegians and meta-analysis in 11,571 subjects indicate that variants in the hepatocyte nuclear factor 4 alpha (HNF4A) P2 region are associated with type 2 diabetes in Scandinavians.

[PMID 17894829] Gene-gene interactions between HNF4A and KCNJ11 in predicting Type 2 diabetes in women.

[PMID 18162503OA-icon.png] Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans.

[PMID 18332101] Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes.

[PMID 18340007OA-icon.png] Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia.

[PMID 18498634OA-icon.png] The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies.

[PMID 18654034] A common P2 promoter polymorphism of the hepatocyte nuclear factor-4alpha gene is associated with insulin secretion in non-obese Japanese with type 2 diabetes.

[PMID 18728231OA-icon.png] Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies.

[PMID 19915572OA-icon.png] Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

[PMID 20079163] Effect of genetic variants in KCNJ11, ABCC8, PPARG and HNF4A loci on the susceptibility of type 2 diabetes in Chinese Han population.

[PMID 20361036OA-icon.png] Gene-gene interactions lead to higher risk for development of type 2 diabetes in an Ashkenazi Jewish population.

[PMID 21062274] Association of novel variants in the hepatocyte nuclear factor 4A gene with maturity onset diabetes of the young and early onset type 2 diabetes.