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rs2165870

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2 2x higher risk for post-operative nausea
(A;G) 2 2x higher risk for post-operative nausea
(G;G) 0
ReferenceGRCh38 38.1/141
Chromosome1
Position239622120
GeneCHRM3
is asnp
is mentioned by
dbSNPrs2165870
ebirs2165870
HLIrs2165870
Exacrs2165870
Varsomers2165870
Maprs2165870
PheGenIrs2165870
hapmaprs2165870
1000 genomesrs2165870
hgdprs2165870
ensemblrs2165870
gopubmedrs2165870
geneviewrs2165870
scholarrs2165870
googlers2165870
pharmgkbrs2165870
gwascentralrs2165870
openSNPrs2165870
23andMers2165870
23andMe allrs2165870
SNP Nexus

SNPshotrs2165870
SNPdbers2165870
MSV3drs2165870
GWAS Ctlgrs2165870
GMAF0.2397
Max Magnitude2
? (A;A) (A;G) (G;G) 28
rs2165870 is a SNP in or near the promoter region of the muscarinic acetylcholine receptor 3 subtype CHRM3 gene on ch 1.

A GWAS study of 300+ patients exhibiting post-operative nausea found that carriers of rs2165870(A) alleles were at 2.3x higher risk for nausea (CI: 1.36 - 4, p = 0.002).[PMID 21694509]

rs2355230 is said to be a perfect proxy (r2 = 1) for rs2165870. [PMID 17903301OA-icon.png] Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study.