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rs2191349

From SNPedia

Orientationplus
Stabilizedplus
Make rs2191349(G;G)
Make rs2191349(G;T)
Make rs2191349(T;T)
ReferenceGRCh38 38.1/141
Chromosome7
Position15024684
GeneLOC100128217
is asnp
is mentioned by
dbSNPrs2191349
ebirs2191349
HLIrs2191349
Exacrs2191349
Varsomers2191349
Maprs2191349
PheGenIrs2191349
hapmaprs2191349
1000 genomesrs2191349
hgdprs2191349
ensemblrs2191349
gopubmedrs2191349
geneviewrs2191349
scholarrs2191349
googlers2191349
pharmgkbrs2191349
gwascentralrs2191349
openSNPrs2191349
23andMers2191349
23andMe allrs2191349
SNP Nexus

SNPshotrs2191349
SNPdbers2191349
MSV3drs2191349
GWAS Ctlgrs2191349
GMAF0.4504
Max Magnitude
? (G;G) (G;T) (T;T) 28
GWAS snp
PMID [PMID 20081858OA-icon.png]
Trait Fasting glucose-related traits
Title New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Risk Allele T
P-val 3E-17
Odds Ratio None None


OMIM613462
Desc
Variant
Relatedalso
[PMID 21887289OA-icon.png] Glucose-Raising Genetic Variants in MADD and ADCY5 Impair Conversion of Proinsulin to Insulin

[PMID 20043853OA-icon.png] Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus.

[PMID 20870969OA-icon.png] Genetic predisposition to long-term nondiabetic deteriorations in glucose homeostasis: Ten-year follow-up of the GLACIER study.

[PMID 21278902OA-icon.png] Genetic risk profiling for prediction of type 2 diabetes.

GWAS snp
PMID [PMID 22581228OA-icon.png]
Trait
Title A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Risk Allele
P-val 3E-21
Odds Ratio None None


GET Evidence
rs2191349
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.59375
summary



[PMID 22698489OA-icon.png] Nonfasting glucose, ischemic heart disease, and myocardial infarction: a Mendelian randomization study.


[PMID 23462794OA-icon.png] Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets.