Have questions? Visit https://www.reddit.com/r/SNPedia

rs2200733(C;C)

From SNPedia

0.86x decreased risk of Atrial Fibrillation
Is agenotype
ofrs2200733
GeneLOC729065
Chromosome4
Position110,789,013
mentionedby
Magnitude1.9
ReputeGood
Geno Mag Summary
(C;C) 1.9 0.86x decreased risk of Atrial Fibrillation
(C;T) 3 1.4x increased risk of Atrial Fibrillation and ischemic stroke.
(T;T) 3 1.5x increased risk of Atrial Fibrillation and ischemic stroke.

This is the normal version which makes the heart form properly and makes people less likely to get Atrial Fibrillation (quivering of the top chambers of the heart caused by chaotic electrical signals) and less likely to have an Ischemic Stroke (blocked blood flow to the brain). But also check the other SNP nearby (rs10033464) which slightly affects Atrial Fibrillation too. 23andMe gave this a 4 star confidence rating as it has been heavily studied. It has been confirmed in Europeans and Asians.