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rs2205960

From SNPedia

Orientationplus
Stabilizedplus
Make rs2205960(G;G)
Make rs2205960(G;T)
Make rs2205960(T;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position173222336
is asnp
is mentioned by
dbSNPrs2205960
ebirs2205960
HLIrs2205960
Exacrs2205960
Varsomers2205960
Maprs2205960
PheGenIrs2205960
hapmaprs2205960
1000 genomesrs2205960
hgdprs2205960
ensemblrs2205960
gopubmedrs2205960
geneviewrs2205960
scholarrs2205960
googlers2205960
pharmgkbrs2205960
gwascentralrs2205960
openSNPrs2205960
23andMers2205960
23andMe allrs2205960
SNP Nexus

SNPshotrs2205960
SNPdbers2205960
MSV3drs2205960
GWAS Ctlgrs2205960
GMAF0.191
Max Magnitude
? (G;G) (G;T) (T;T) 28
[PMID 19357697OA-icon.png] Association of BANK1 and TNFSF4 with systemic lupus erythematosus in Hong Kong Chinese.
GWAS snp
PMID [PMID 19838193]
Trait Systemic lupus erythematosus
Title Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
Risk Allele A
P-val 3E-32
Odds Ratio 1.46 [1.37-1.56]


[PMID 19778912OA-icon.png] Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis

OMIM152700
Desc
Variant
Relatedalso
[PMID 22422496OA-icon.png] Independent Replication and Metaanalysis of Association Studies Establish TNFSF4 as a Susceptibility Gene Preferentially Associated with the Subset of Anticentromere-positive Patients with Systemic Sclerosis

[PMID 19838195OA-icon.png] A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

[PMID 21379322OA-icon.png] Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.

[PMID 21408207OA-icon.png] Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.


GET Evidence
rs2205960
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.164062
summary



GWAS snp
PMID [PMID 23273568OA-icon.png]
Trait Systemic lupus erythematosus
Title Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
Risk Allele T
P-val 3E-12
Odds Ratio 1.36


[PMID 23622253] Association of TNFSF4 polymorphisms with susceptibility to primary Sjögren's syndrome and primary biliary cirrhosis in a Chinese Han population


[PMID 23874208OA-icon.png] Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4


[PMID 22820624] Associations between TNFSF4 and TRAF1-C5 gene polymorphisms and systemic lupus erythematosus: a meta-analysis.


[PMID 22850862] Association of TNFSF4 polymorphisms with systemic lupus erythematosus: a meta-analysis.


[PMID 27519474] TNFSF4 polymorphisms are associated with systemic lupus erythematosus in the Malaysian population.