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rs2207418

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 2 ~2x increased risk of heart failure, at least in Amish
(C;T) 1.5 1.5x increased risk for heart failure, at least in Amish
(T;T) 0
ReferenceGRCh38 38.1/141
Chromosome20
Position11194255
is asnp
is mentioned by
dbSNPrs2207418
ebirs2207418
HLIrs2207418
Exacrs2207418
Varsomers2207418
Maprs2207418
PheGenIrs2207418
hapmaprs2207418
1000 genomesrs2207418
hgdprs2207418
ensemblrs2207418
gopubmedrs2207418
geneviewrs2207418
scholarrs2207418
googlers2207418
pharmgkbrs2207418
gwascentralrs2207418
openSNPrs2207418
23andMers2207418
23andMe allrs2207418
SNP Nexus

SNPshotrs2207418
SNPdbers2207418
MSV3drs2207418
GWAS Ctlgrs2207418
GMAF0.3609
Max Magnitude2
? (C;C) (C;T) (T;T) 28
rs2207418 is a SNP located in a 'gene desert' region of ch 20p12.

In an Amish founder population of 851 individuals, the rs2207418(C) allele was associated with cardiac hypertrophy, increased risk of heart failure (relative risk 1.85, CI: 1.2 - 2.7, p = 0.0019), and increased mortality (hazard risk 1.5, CI: 1.2 - 1.9, p = 0.0004).[PMID 21348951OA-icon.png]