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rs2236196

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 common in complete genomics
Make rs2236196(A;G)
Make rs2236196(G;G)
ReferenceGRCh38 38.1/141
Chromosome20
Position63346204
GeneCHRNA4
is asnp
is mentioned by
dbSNPrs2236196
ebirs2236196
HLIrs2236196
Exacrs2236196
Varsomers2236196
Maprs2236196
PheGenIrs2236196
hapmaprs2236196
1000 genomesrs2236196
hgdprs2236196
ensemblrs2236196
gopubmedrs2236196
geneviewrs2236196
scholarrs2236196
googlers2236196
pharmgkbrs2236196
gwascentralrs2236196
openSNPrs2236196
23andMers2236196
23andMe allrs2236196
SNP Nexus

SNPshotrs2236196
SNPdbers2236196
MSV3drs2236196
GWAS Ctlgrs2236196
GMAF0.337
Max Magnitude0
OMIM118504
DescCHOLINERGIC RECEPTOR, NEURONAL NICOTINIC, ALPHA POLYPEPTIDE 4; CHRNA4
Variant
Relatedalso



[PMID 19482438] Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence


[PMID 22309839] Association study of 45 candidate genes in nicotine dependence in Han Chinese


[PMID 15154117OA-icon.png] A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men.


[PMID 17135278OA-icon.png] Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs.


[PMID 17503330OA-icon.png] A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence.


[PMID 17768273] CHRNA4 and tobacco dependence: from gene regulation to treatment outcome.


[PMID 18165968OA-icon.png] Identification of pharmacogenetic markers in smoking cessation therapy.


[PMID 18534558OA-icon.png] Gene-gene interactions among CHRNA4, CHRNB2, BDNF, and NTRK2 in nicotine dependence.


[PMID 18571741OA-icon.png] Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research.


[PMID 18593715OA-icon.png] Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation.


[PMID 18618000OA-icon.png] A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.


[PMID 18698231OA-icon.png] Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues.


[PMID 19029397OA-icon.png] Nicotinic receptor gene variants influence susceptibility to heavy smoking.


[PMID 19238175OA-icon.png] New insights into the genetics of addiction.


[PMID 19259974OA-icon.png] Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.


[PMID 19693267OA-icon.png] Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.


[PMID 21445957OA-icon.png] Association of CHRNA4 polymorphisms with smoking behavior in two populations.


[PMID 22180580] Association Between Nicotinic Acetylcholine Receptor Single Nucleotide Polymorphisms and Smoking Cessation.


GET Evidence
rs2236196
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.537736
summary